Focusing on adenosine receptors as a potential targeted therapy in human diseases

WI Effendi, T Nagano, K Kobayashi, Y Nishimura - Cells, 2020 - mdpi.com
… biological features of each adenosine receptor as the basis of ligand production and
describes clinical studies of adenosine receptor-associated pharmaceuticals in human diseases. …

Adenosine receptors as drug targets—what are the challenges?

JF Chen, HK Eltzschig, BB Fredholm - Nature reviews Drug discovery, 2013 - nature.com
… that can be safely targeted by adenosine receptor agonists or antagonists. … adenosine
receptors, which represent pharmacological targets for the treatment of several human diseases

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

G Haskó, J Linden, B Cronstein, P Pacher - Nature reviews Drug …, 2008 - nature.com
… activation is able to stimulate the degranulation of human mast cells 44 , the observation of
adenosine receptor activation strongly implicates human mast-cell adenosine receptors as …

Adenosine receptors in health and disease

S Gessi, S Merighi, K Varani, PA Borea - Advances in pharmacology, 2011 - Elsevier
… molecular characterization of adenosine receptors, which have … be speculated that adenosine
A 1 , A 2A , A 2B , and A 3 receptor-… of adenosine receptors’ role in health and disease. …

Adenosine receptors as therapeutic targets

KA Jacobson, ZG Gao - Nature reviews Drug discovery, 2006 - nature.com
… and antagonists of adenosine receptors have been discovered, … the roles of the various
adenosine receptor subtypes, and in the … of adenosine receptor modulators considerably closer. …

Adenosine and adenosine receptors in the pathomechanism and treatment of respiratory diseases

G Vass, I Horvath - Current medicinal chemistry, 2008 - ingentaconnect.com
… of adenosine receptor subtypes and their role in the pathomechanism of respiratory diseases
… This review aims to summarize the role of adenosine and adenosine receptors in asthma …

[HTML][HTML] Adenosine receptors and brain diseases: neuroprotection and neurodegeneration

CV Gomes, MP Kaster, AR Tomé, PM Agostinho… - … et Biophysica Acta (BBA …, 2011 - Elsevier
… In spite of this current mechanistic uncertainty, it seems evident that targeting adenosine
receptors might indeed … This article is part of a Special Issue entitled: "Adenosine Receptors". …

Adenosine receptors and inflammation

MR Blackburn, CO Vance, E Morschl… - Adenosine receptors in …, 2009 - Springer
diseases. This review is designed to summarize the current status of adenosine receptor
to review the contribution of adenosine and adenosine receptors to the regulation of key …

[图书][B] Adenosine receptors in health and disease

CN Wilson, SJ Mustafa - 2009 - Springer
… Since the first description of adenosine receptors 30 years ago, based on the valuable
scientific discoveries and contributions by individuals working in the field of adenosine receptor (…

Introduction to adenosine receptors as therapeutic targets

KA Jacobson - Adenosine receptors in health and disease, 2009 - Springer
Adenosine acts as a cytoprotective modulator in response to … subtypes of G protein-coupled
adenosine receptors (ARs): A … lasting in the body than adenosine, have potential therapeutic …