[HTML][HTML] Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
H Li, Y Yang, W Hong, M Huang, M Wu… - Signal transduction and …, 2020 - nature.com
… of the three major genome editing technologies (ZFNs, … reagents as gene editing tools in
various human diseases and … applying genome editing platforms for disease treatment and …
various human diseases and … applying genome editing platforms for disease treatment and …
[HTML][HTML] CRISPR-mediated genome editing and human diseases
… 9) genome editing has been used to correct disease-causing … In addition to genetic diseases,
CRISPR/Cas9 gene editing … 5, the programmed death 1 gene, or the creation of chimeric …
CRISPR/Cas9 gene editing … 5, the programmed death 1 gene, or the creation of chimeric …
Genome editing: a new approach to human therapeutics
M Porteus - Annual review of pharmacology and toxicology, 2016 - annualreviews.org
… (genome editing) has been a powerful research tool. In the past decade, the tools and expertise
for using genome editing in human … a strategy to treat human disease. The fundamental …
for using genome editing in human … a strategy to treat human disease. The fundamental …
Ethics of human genome editing
BS Coller - Annual review of medicine, 2019 - annualreviews.org
… In summary, the NAS/NAM report (31) identified a number of diseases that might benefit from
somatic genome editing (see table 4-1, p. 92) and recommended that (a) the current ethical …
somatic genome editing (see table 4-1, p. 92) and recommended that (a) the current ethical …
The promise and challenge of therapeutic genome editing
JA Doudna - Nature, 2020 - nature.com
… Genome editing, which involves the precise manipulation of cellular DNA sequences to …
both improve our understanding of human genetics and cure genetic disease. Here I discuss the …
both improve our understanding of human genetics and cure genetic disease. Here I discuss the …
[PDF][PDF] A new era of gene editing for the treatment of human diseases
KC Mandip, CJ Steer - Swiss medical weekly, 2019 - smw.ch
… gene editing components are also discussed. Lastly, we review examples of human diseases
that are not only amenable to gene editing … century of genetic correction and gene repair. …
that are not only amenable to gene editing … century of genetic correction and gene repair. …
[HTML][HTML] Genome editing: A perspective on the application of CRISPR/Cas9 to study human diseases
DR Rodríguez‑Rodríguez… - International …, 2019 - spandidos-publications.com
… advances in genome editing allow the manipulation of any gene at … Genome editing is a
powerful tool for biomedical research and provides hope for correcting some inherited diseases…
powerful tool for biomedical research and provides hope for correcting some inherited diseases…
CRISPR/Cas system: a game changing genome editing technology, to treat human genetic diseases
… CRISPR/Cas9 editing technology can use in disease model to study the … genome editing
in vivo and its implications for the future of human genetic disease treatment as well as genome …
in vivo and its implications for the future of human genetic disease treatment as well as genome …
Genome-editing technologies: principles and applications
… human disease, and promoting exciting new possibilities for … Here we review key principles
of genome editing, … implementation of the current suite of genome-modifying tools. We also …
of genome editing, … implementation of the current suite of genome-modifying tools. We also …
Genome editing in cardiovascular diseases
A Strong, K Musunuru - Nature Reviews Cardiology, 2017 - nature.com
… cardiovascular disease research and the prospect of in vivo genome-editing therapies in …
of genome-editing tools that will need to be addressed if cardiovascular genome editing is to …
of genome-editing tools that will need to be addressed if cardiovascular genome editing is to …
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