[HTML][HTML] Genetic causes of human heart failure

H Morita, J Seidman, CE Seidman - The Journal of clinical …, 2005 - Am Soc Clin Investig
… of human gene mutations provide a window into the complex processes of cardiac remodeling
and heart failure… novel therapeutic targets for genetic and acquired causes of heart failure. …

Sympathetic nervous system activation in human heart failure: clinical implications of an updated model

JS Floras - Journal of the American College of cardiology, 2009 - jacc.org
Heart failure due to left ventricular systolic dysfunction has … vagal control of heart rate is
impaired early in heart failure, a … function; and 2) human heart failure is characterized by rapidly …

The gene expression fingerprint of human heart failure

FL Tan, CS Moravec, J Li… - Proceedings of the …, 2002 - National Acad Sciences
… Affymetrix HuFl 6800 GeneChips containing 6,606 unique genes were used in this study
with one GeneChip used for each human heart sample. To make comparisons across …

Altered myocardial force-frequency relation in human heart failure.

LA Mulieri, G Hasenfuss, B Leavitt, PD Allen… - Circulation, 1992 - Am Heart Assoc
… DCM heart failure compared with patients without heart failure.3 … In subjects with DCM
heart failure, pacing tachycardia … activity in patients with DCM heart failure. With moderate to …

Myosin heavy chain gene expression in human heart failure.

K Nakao, W Minobe, R Roden… - The Journal of …, 1997 - Am Soc Clin Investig
… Given the potential physiological consequences of cardiac MyHC isoform shifts, we
determined MyHC gene expression in human heart failure where cardiac contractility is impaired …

Natriuretic peptide system in human heart failure.

CM Wei, DM Heublein, MA Perrella, A Lerman… - Circulation, 1993 - Am Heart Assoc
… Nonetheless, increases in circulating ANP may also involve reduced hepatic and renal
clearance secondary to impaired hepatic and renal function in human heart failure.'7 The …

Expression of inducible nitric oxide synthase in human heart failure

GA Haywood, PS Tsao, HE Von Der Leyen, MJ Mann… - Circulation, 1996 - Am Heart Assoc
… Results of the present study provide evidence that heart failure is associated with induction
heart failure secondary to dilated cardiomyopathy, ischemic heart disease, or valvular heart

Increased myocardial NADPH oxidase activity in human heart failure

C Heymes, JK Bendall, P Ratajczak, AC Cave… - Journal of the American …, 2003 - jacc.org
… oxidase is expressed in the human myocardium or if it has any role in human heart failure. …
human heart and that it is likely to be an important source of increased cardiac ROS in human

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure

T Thum, P Galuppo, C Wolf, J Fiedler, S Kneitz… - Circulation, 2007 - Am Heart Assoc
… to be regulated in human heart failure reported by Olson’s … of end-stage human heart failure
because during initiation and … activated compared with the failing heart (see Reference 1 …

Calcineurin and human heart failure

HW Lim, JD Molkentin - Nature medicine, 1999 - nature.com
… in human heart failure. To determine if calcineurin was associated with human heart failure,
… bypass the technical difficulties associated with human tissue samples. This assay involves …