Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

BY Hu, JP Weick, J Yu, LX Ma… - Proceedings of the …, 2010 - National Acad Sciences
… For the promise of human induced pluripotent stem cells (iPSCs) to be realized, it … cells of
various lineages. Here, we have directly compared the neural-differentiation capacity of human

[HTML][HTML] Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

A Chandrasekaran, HX Avci, A Ochalek, LN Rösingh… - Stem cell …, 2017 - Elsevier
… two neural induction methods to generate neural progenitor cells (NPCs); (2D neural induction
and 3D neural induction). … positive neural progenitor cells in all of our examined cell lines. …

Survival and differentiation of transplanted neural stem cells derived from human induced pluripotent stem cells in a rat stroke model

MB Jensen, H Yan, R Krishnaney-Davison… - Journal of Stroke and …, 2013 - Elsevier
stem cells has shown promise in stroke models, neural stem cells (NSCs) derived from human
induced pluripotent stem cells (iPSCs) have advantages over other cell types. We studied …

Human induced pluripotent stem cells derived from fetal neural stem cells successfully undergo directed differentiation into cartilage

SP Medvedev, EV Grigor'eva… - Stem cells and …, 2011 - liebertpub.com
… of iPS cells have not been yet sufficiently elaborated. In this work, we derived human iPS cells
from fetal neural stem (FNS) cells … expressing the human OCT4 gene. We have shown that …

Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery …

T Yuan, W Liao, NH Feng, YL Lou, X Niu… - Stem cell research & …, 2013 - Springer
… properties and functions of nerve cells. Later, Zhou and … human ESCs differentiation into
neural stem cells, but efficiency was low, and the survival capacity of RA-induced neuronal cells

Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord

D Sareen, G Gowing, A Sahabian… - Journal of …, 2014 - Wiley Online Library
… Our results describe a new source of human neural progenitor cells that do not have the
supply, expansion, and ethical concerns of fNPCs, and hence could be ideal for stem cell-based …

Neural stem cells and human induced pluripotent stem cells to model rare CNS diseases

L De Filippis, C Zalfa, D Ferrari - CNS & Neurological …, 2017 - ingentaconnect.com
neural cells viability and functionality. The isolation and expansion in vitro of embryonic (ESC)
and fetal neural stem cells (NSC) from human tissue … of induced pluripotent stem cell (iPS) …

Altered WNT signaling in human induced pluripotent stem cell neural progenitor cells derived from four schizophrenia patients

A Topol, S Zhu, N Tran, A Simone… - Biological …, 2015 - biologicalpsychiatryjournal.com
… Figure 1RNA sequencing comparisons of control and schizophrenia human induced
pluripotent stem cell (hiPSC) neural progenitor cells (NPCs). (A) Multidimensional scaling of RNA …

Establishment of human neural progenitor cells from human induced pluripotent stem cells with diverse tissue origins

H Fukusumi, T Shofuda, Y Bamba… - Stem cells …, 2016 - Wiley Online Library
Human neural progenitor cells (hNPCs) have … of human induced pluripotent stem cell (hiPSC)
clones. Here, 21 hiPSC clones derived from human dermal fibroblasts, cord blood cells, …

Differentiation of human induced pluripotent stem cells (iPSCs) into an effective model of forebrain neural progenitor cells and mature neurons

S Bell, NC Hettige, H Silveira, H Peng, H Wu, M Jefri… - Bio …, 2019 - bio-protocol.org
neural progenitor cells (NPCs) and neurons, whereby neural rosettes are generated from
stem cellsNeural progenitor cells can be maintained as long-term cultures, or differentiated …