[HTML][HTML] From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma
V Ratushny, MD Gober, R Hick… - The Journal of …, 2012 - Am Soc Clin Investig
… One recent observation in a human keratinocyte cell line (HaCaT cells) demonstrated
that the Fyn kinase is an effector of oncogenic Ras (61). In these studies, oncogenic Hras …
that the Fyn kinase is an effector of oncogenic Ras (61). In these studies, oncogenic Hras …
Insulin-like growth factors are mitogenic for human keratinocytes and a squamous cell carcinoma
EK Neely, VB Morhenn, RL Hintz, DM Wilson… - Journal of investigative …, 1991 - Elsevier
… N ormal adult human keratinocytes in monolayer culture and SCL-1, a skin-derived
squamous-cell carcinoma cell line, were investigated for the expression of receptors for insulinlike …
squamous-cell carcinoma cell line, were investigated for the expression of receptors for insulinlike …
Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer
… cells into squamous carcinoma cells (SCC), we compared the response to ultraviolet B
radiation (UVB) of normal human epidermal keratinocytes (… genes in keratinocytes fall into three …
radiation (UVB) of normal human epidermal keratinocytes (… genes in keratinocytes fall into three …
E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formation
L Endo-Munoz, A Dahler, N Teakle, D Rickwood… - Cancer research, 2009 - AACR
… Given the association of E2F7b with growth inhibition in human keratinocytes, we examined
whether E2F7a or E2F7b was preferentially expressed in KSCs, which we have shown …
whether E2F7a or E2F7b was preferentially expressed in KSCs, which we have shown …
Detection of transforming growth factor alpha in normal, malignant, and hyperproliferative human keratinocytes.
AB Gottlieb, CK Chang, DN Posnett, B Fanelli… - The Journal of …, 1988 - rupress.org
… normal and malignant keratinocytes. Formalin-… Keratinocytes in eight nodular basal cell
carcinomas (a and b), one morpheic basal cell carcinoma (d), and one squamous cell carcinoma …
carcinomas (a and b), one morpheic basal cell carcinoma (d), and one squamous cell carcinoma …
Specific betapapillomaviruses associated with squamous cell carcinoma of the skin inhibit UVB-induced apoptosis of primary human keratinocytes
L Struijk, E van der Meijden… - Journal of general …, 2008 - microbiologyresearch.org
… Primary human keratinocytes transduced with E6 and E7 of … HPV8- and HPV20-expressing
keratinocytes in particular … when expressed in primary human keratinocytes. Infections with …
keratinocytes in particular … when expressed in primary human keratinocytes. Infections with …
[HTML][HTML] XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas
HR Rezvani, AL Kim, R Rossignol, N Ali… - The Journal of …, 2011 - Am Soc Clin Investig
… Taken together, our results demonstrate that XPC silencing in normal human keratinocytes
leads to altered metabolism, which resembles the metabolic signature of most cancer cells. …
leads to altered metabolism, which resembles the metabolic signature of most cancer cells. …
The genetic basis of human keratinocyte immortalisation in squatnous cell carcinoma development: The role of telomerase reactivation
EK Parkinson, RF Newbold, WN Keith - European Journal of Cancer, 1997 - Elsevier
… the immortal phenotype in a naturally occuring human tumour, we established keratinocyte
cultures from all stages of head and neck squamous cell carcinoma development (SCC-HN) …
cultures from all stages of head and neck squamous cell carcinoma development (SCC-HN) …
TRPC channels determine human keratinocyte differentiation: new insight into basal cell carcinoma
… Indeed, our study is the first to characterize I SOC in human keratinocytes. Biophysical
characteristics of keratinocyte I SOC , including pharmacology and ion selectivity, were similar to …
characteristics of keratinocyte I SOC , including pharmacology and ion selectivity, were similar to …
Production of interleukin-1 and interleukin-6 by human keratinocytes and squamous cell carcinoma cell lines
… on a wide range of cell types (reviewed in [7]) … keratinocytes [8] and IL-6 by keratinocyte
cell lines [9]. In this paper we confirm that cultured keratinocytes and squamous cell carcinoma (…
cell lines [9]. In this paper we confirm that cultured keratinocytes and squamous cell carcinoma (…
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