Models and methods for predicting drug transfer into human milk

JC Fleishaker - Advanced drug delivery reviews, 2003 - Elsevier
drug transfer into milk in … drug partitioning between milk and plasma. In vivo studies may
be necessary to assess active processes that may either transport drugs into or out of breast milk

[HTML][HTML] Drug distribution in human milk

KF Ilett, JH Kristensen… - Australian …, 1997 - australianprescriber.tg.org.au
… during maternal drug therapy is an individualised risk:benefit analysis. An infant's exposure
depends on drug transfer into milk, daily milk intake and the bioavailability of the drug in the …

Determinants of drug transfer into human milk

EJ Begg - Drugs and human lactation, 1996 - Elsevier
… This chapter discusses three major components that affect drug transfer into human milk and
… The passage of drug from maternal ingestion to the infant begins with the ingestion of drug

The transfer of drugs and other chemicals into human milk

Committee on Drugs - Pediatrics, 2001 - publications.aap.org
… of the drug, the maternal dose and mode of administration, the concentration of the drug in
milk and … regarding drug transfer into human milk and the potential or actual risk to the infant. …

The transfer of drugs and therapeutics into human breast milk: an update on selected topics

HC Sachs, Committee on Drugs, DAC Frattarelli… - …, 2013 - publications.aap.org
… are excreted in clinically significant amounts into human milk, and the presence of a drug
in human milk may not pose a risk for the infant. To weigh the risks and benefits of …

Transfer of drugs and other chemicals into human milk

Committee on Drugs - Pediatrics, 1989 - publications.aap.org
… the transfer of drugs and chemicals into human milk. This … agents transferred into human milk
and their possible effects … that it is not transferred into human milk or that it does not have an …

Drugs and chemicals in human milk

CM Berlin, GG Briggs - Seminars in Fetal and Neonatal Medicine, 2005 - Elsevier
… This article presents an introduction to the pharmacology of the transfer of drugs into milk,
discusses the importance of the infant's age in assessing safety and presents a number of …

Drug excretion into breast milk—overview

S Ito, A Lee - Advanced drug delivery reviews, 2003 - Elsevier
… constitute other important groups of compounds potentially contaminating human milk.
However, our knowledge of drug transfer in the mammary gland and its clinical consequences …

The transfer of drugs and other chemicals into human milk

Committee on Drugs - Pediatrics, 1994 - publications.aap.org
transfer of drugs and chemicals into human milk continues to become available. This current
statement is intended to revise the lists of agents transferred into human milkhuman milk or …

Principles of drug transfer into breast milk and drug disposition in the nursing infant

RL Breitzka, TL Sandritter… - Journal of human …, 1997 - journals.sagepub.com
… Changes in breast milk composition also influence drug transfer and the M/P ratio accuracy.
Breast milk protein, fat, and pH vary according to postpartum time, time of day, and duration …