Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss
RR Ager, JL Davis, A Agazaryan, F Benavente… - …, 2015 - Wiley Online Library
… We previously reported that intrahippocampal transplantation of murine neural stem cells
(… neuronal loss. These promising findings prompted us to examine a human neural stem cell …
(… neuronal loss. These promising findings prompted us to examine a human neural stem cell …
Laminin enhances the growth of human neural stem cells in defined culture media
… Human neural stem cells (hNSC) have the potential to provide novel cell-based therapies for
… In vivo, stem cells reside in distinct microenvironments or niches that are responsible for the …
… In vivo, stem cells reside in distinct microenvironments or niches that are responsible for the …
Human neural stem cells induce functional myelination in mice with severe dysmyelination
N Uchida, K Chen, M Dohse, KD Hansen… - Science translational …, 2012 - science.org
… We show that purified, expanded, and banked fetal human neural stem cells generate … to
extend the potential window for human CNS stem cell therapy to patients with myelin disorders …
extend the potential window for human CNS stem cell therapy to patients with myelin disorders …
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
DE Redmond Jr, KB Bjugstad… - Proceedings of the …, 2007 - National Acad Sciences
… Stem cells have been widely assumed to be capable of replacing lost or damaged cells
in a … We report that undifferentiated human neural stem cells (hNSCs) implanted into 1-methyl-4-…
in a … We report that undifferentiated human neural stem cells (hNSCs) implanted into 1-methyl-4-…
Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat
… -term mitogen-expanded human stem cells. As these neurons … For example, human stem
cell–derived cholinergic neurons … -expanded primary fetal human neural stem cells (hNSCs) to …
cell–derived cholinergic neurons … -expanded primary fetal human neural stem cells (hNSCs) to …
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
… transformation of human neural stem cells (NSCs), but not mesenchymal stem cells. PTEN-…
and instates ‘aggressiveness’ in human glioblastoma stem cells. In a large clinical database…
and instates ‘aggressiveness’ in human glioblastoma stem cells. In a large clinical database…
Attomole quantification and global profile of RNA modifications: Epitranscriptome of human neural stem cells
M Basanta-Sanchez, S Temple, SA Ansari… - Nucleic acids …, 2016 - academic.oup.com
… human pluripotent stem cell-derived, neural stem cells. A wide variety of RNA modifications
were detected at levels as low as 0.0023 pg/μl, 64.09 attomoles. These results illustrate the …
were detected at levels as low as 0.0023 pg/μl, 64.09 attomoles. These results illustrate the …
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease
T Yasuhara, N Matsukawa, K Hara, G Yu… - Journal of …, 2006 - Soc Neuroscience
… In this study, we evaluated human HB1.F3 neural stem cells (NSCs) as graft source for PD.
… F3 cells, a human fetal-derived neural stem cell line, as described previously in detail, were …
… F3 cells, a human fetal-derived neural stem cell line, as described previously in detail, were …
A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes
L De Filippis, G Lamorte, EY Snyder, A Malgaroli… - Stem …, 2007 - academic.oup.com
… type cell lines currently available is insufficient. Here we report the establishment of a stable
human neural stem cell line (immortalized human … These cells demonstrate three- to fourfold …
human neural stem cell line (immortalized human … These cells demonstrate three- to fourfold …
Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia
… Stem cell transplantation may recover functional deficit by replacing damaged brain. In this
study, we attempted to test whether the human neural stem cells … viabilities of human NSCs in …
study, we attempted to test whether the human neural stem cells … viabilities of human NSCs in …