Induction of human neuronal cells by defined transcription factors
… of transcription factors could induce a neuronal fate in human … have identified a combination
of transcription factors that are capable of converting human fibroblasts directly into neurons. …
of transcription factors that are capable of converting human fibroblasts directly into neurons. …
Transcription factor-based strategies to generate neural cell types from human pluripotent stem cells
I Canals, E Quist, H Ahlenius - Cellular Reprogramming, 2021 - liebertpub.com
… to study human neural cells; however, in combination with animal studies and observations
in postmortem tissue, they represent powerful tools to understand functionality of brain cells …
in postmortem tissue, they represent powerful tools to understand functionality of brain cells …
Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
… suggests that the lncRNAs play a key role in neural cell fate specification. … identified lncRNAs
essential for the maintenance of pluripotency and neuronal differentiation in human cells …
essential for the maintenance of pluripotency and neuronal differentiation in human cells …
Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS
I Jakovcevski, N Zecevic - Journal of Neuroscience, 2005 - Soc Neuroscience
… human brain. In this study, we examine whether the expression of Olig1 and Olig2 transcription
factors … the onset and developmental progression of OL lineage in the human fetal CNS. …
factors … the onset and developmental progression of OL lineage in the human fetal CNS. …
[HTML][HTML] The human transcription factors
… to regulation of transcription. This review considers how TFs are identified and functionally
characterized, principally through the lens of a catalog of over 1,600 likely human TFs and …
characterized, principally through the lens of a catalog of over 1,600 likely human TFs and …
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene
P Pruunsild, M Sepp, E Orav, I Koppel… - Journal of …, 2011 - Soc Neuroscience
… of this promoter by neuronal activity. Together, the results of this study … identified the cis-elements
and transcription factors regulating neuronal activity-dependent transcription of human …
and transcription factors regulating neuronal activity-dependent transcription of human …
Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways
A Serre, EY Snyder, J Mallet… - Stem Cells and …, 2011 - liebertpub.com
… Because some of these markers can have expression patterns that extend beyond one neural
cell type, often dual marker expression was used in this study to clarify specific neural cell …
cell type, often dual marker expression was used in this study to clarify specific neural cell …
Neuronal transcription factors induce conversion of human glioma cells to neurons and inhibit tumorigenesis
J Zhao, H He, K Zhou, Y Ren, Z Shi, Z Wu, Y Wang… - 2012 - journals.plos.org
… It is well known that neurons are terminally differentiated cells … glioma cells to become neurons
by introducing transcription factors. … of induced neuronal (iN) cells from glioma cells by the …
by introducing transcription factors. … of induced neuronal (iN) cells from glioma cells by the …
Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers
G Miskinyte, M Grønning Hansen, E Monni, M Lam… - PLoS …, 2018 - journals.plos.org
… cells have been incompletely characterized. Here we have used transcription factor (TF) …
aim to induce rapid differentiation of human ES cells to layer-specific cortical neurons (hES-iNs). …
aim to induce rapid differentiation of human ES cells to layer-specific cortical neurons (hES-iNs). …
… generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors
… We previously reported that mouse and human fibroblasts can be directly reprogrammed
into dopaminergic-like neuronal cells by the combined expression of the three cell lineage TFs …
into dopaminergic-like neuronal cells by the combined expression of the three cell lineage TFs …
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