Mechanical control of human osteoblast apoptosis and proliferation in relation to differentiation
FAA Weyts, B Bosmans, R Niesing, J Leeuwen… - Calcified Tissue …, 2003 - Springer
… chemical background of mechanical regulation of bone mass and architecture has been
the focus of several studies using cultured bone cells. Bone cells can respond to various …
the focus of several studies using cultured bone cells. Bone cells can respond to various …
Mechanical regulation of osteoclastic genes in human osteoblasts
L Kreja, A Liedert, S Hasni, L Claes… - … and biophysical research …, 2008 - Elsevier
… mechanical load influences the expression profile of key factors regulating osteoclastogenesis
in primary human osteoblasts… up-regulated only after intermittent mechanical stimulation. …
in primary human osteoblasts… up-regulated only after intermittent mechanical stimulation. …
Effects of mechanical stress stimulation on function and expression mechanism of osteoblasts
P Liu, J Tu, W Wang, Z Li, Y Li, X Yu… - … in Bioengineering and …, 2022 - frontiersin.org
… stress) on osteoclast and osteoblast function and expression … and osteoblasts in activating
different mechanical transduction … the effects of mechanical stimulation on the regulation and …
different mechanical transduction … the effects of mechanical stimulation on the regulation and …
Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation
LV Harter, KA Hruska, RL Duncan - Endocrinology, 1995 - academic.oup.com
… Type I collagen is the predominant bone matrix protein produced by the osteoblast. To
determine whether type I collagen is up-regulated in response to cyclic mechanical stimulation, …
determine whether type I collagen is up-regulated in response to cyclic mechanical stimulation, …
Mechanical regulation of bone remodeling
… via a balance between bone formation by osteoblasts and resorption by osteoclasts. These
… mechanical forces, altering bone mass in response to changing conditions. Mechanical …
… mechanical forces, altering bone mass in response to changing conditions. Mechanical …
Mechanical regulation of signaling pathways in bone
… are responsive to mechanical signals, including osteoblasts, osteoclasts, … Several mechanically
regulated intracellular signaling … While the interaction of bone cells with their mechanical …
regulated intracellular signaling … While the interaction of bone cells with their mechanical …
[HTML][HTML] … of multiple forms of mechanical loading to human osteoblasts reveals increased ATP release in response to fluid flow in 3D cultures and differential regulation …
… type(s) of mechanical stimuli induce ATP release and gene activation in human osteoblasts,
we performed an array of experiments using different mechanical stimuli applied to both …
we performed an array of experiments using different mechanical stimuli applied to both …
Mechanotransduction in osteoblast regulation and bone disease
KK Papachroni, DN Karatzas, KA Papavassiliou… - Trends in molecular …, 2009 - cell.com
… by several hormones, growth factors and mechanical cues … Bone cells are responsive to
mechanical stimuli and this is of … activated by mechanical stimulation during osteoblastic growth, …
mechanical stimuli and this is of … activated by mechanical stimulation during osteoblastic growth, …
ERK activation and αvβ3 integrin signaling through Shc recruitment in response to mechanical stimulation in human osteoblasts
FAA Weyts, YS Li, J van Leeuwen… - Journal of cellular …, 2002 - Wiley Online Library
… In conclusion, it is evident from our experiments that mechanical stimuli regulate ERK
signaling in human bone cells, which can provide a cellular mechanism through which bone …
signaling in human bone cells, which can provide a cellular mechanism through which bone …
Mechanically induced ATP release from human osteoblastic cells
M Romanello, B Pani, M Bicego, P D'Andrea - Biochemical and biophysical …, 2001 - Elsevier
… Mechanical perturbations such as … to regulate the specialised functions of many tissues.
We (9) and others (10) have demonstrated recently that mechanical stimulation of osteoblasts in…
We (9) and others (10) have demonstrated recently that mechanical stimulation of osteoblasts in…
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