… chemical background of mechanical regulation of bone mass and architecture has been
the focus of several studies using cultured bone cells. Bone cells can respond to various …

… mechanical load influences the expression profile of key factors regulating osteoclastogenesis
in primary human osteoblasts… up-regulated only after intermittent mechanical stimulation. …

… stress) on osteoclast and osteoblast function and expression … and osteoblasts in activating
different mechanical transduction … the effects of mechanical stimulation on the regulation and …

… Type I collagen is the predominant bone matrix protein produced by the osteoblast. To
determine whether type I collagen is up-regulated in response to cyclic mechanical stimulation, …

… via a balance between bone formation by osteoblasts and resorption by osteoclasts. These
… mechanical forces, altering bone mass in response to changing conditions. Mechanical …

… are responsive to mechanical signals, including osteoblasts, osteoclasts, … Several mechanically
regulated intracellular signaling … While the interaction of bone cells with their mechanical …

… type(s) of mechanical stimuli induce ATP release and gene activation in human osteoblasts,
we performed an array of experiments using different mechanical stimuli applied to both …

… by several hormones, growth factors and mechanical cues … Bone cells are responsive to
mechanical stimuli and this is of … activated by mechanical stimulation during osteoblastic growth, …

… In conclusion, it is evident from our experiments that mechanical stimuli regulate ERK
signaling in human bone cells, which can provide a cellular mechanism through which bone …

… Mechanical perturbations such as … to regulate the specialised functions of many tissues.
We (9) and others (10) have demonstrated recently that mechanical stimulation of osteoblasts in…