Barrier capacity of human placenta for nanosized materials

P Wick, A Malek, P Manser, D Meili… - Environmental …, 2010 - ehp.niehs.nih.gov
… Our study showed a clear size-dependent barrier capacity of a healthy human placenta for
PS nanoparticles, including an analysis of the viability and functionality of the tissue after the …

[HTML][HTML] An advanced human in vitro co-culture model for translocation studies across the placental barrier

L Aengenheister, K Keevend, C Muoth… - Scientific reports, 2018 - nature.com
… In this study a new in vitro co-culture model simulating the human placental barrier was …
Moreover, the barrier capacity of the co-culture was equal to the one of the BeWo layer, …

Growth and function of the normal human placenta

NM Gude, CT Roberts, B Kalionis, RG King - Thrombosis research, 2004 - Elsevier
… The term placental membrane (sometimes called the placental barrier) refers to the layers of
… to have a limited capacity for synthesis of stearic, myristic and lauric acids [40]. Although the …

Placental drug transport‐on‐a‐chip: a microengineered in vitro model of transporter‐mediated drug efflux in the human placental barrier

C Blundell, YS Yi, L Ma, ER Tess… - Advanced …, 2018 - Wiley Online Library
… -on-a-chip model, we first examined whether our microengineered placental tissue had
the capacity to form an effective barrier to soluble molecules and to properly mimic restrictive …

Placenta-on-a-chip: a novel platform to study the biology of the human placenta

JS Lee, R Romero, YM Han, HC Kim… - The Journal of …, 2016 - Taylor & Francis
placental barrier by measuring glucose transport across the trophoblast-endothelial interface
over time. The permeability of the barrier … characteristics of the human placental barrier, but …

[HTML][HTML] Placenta-on-a-Chip as an In Vitro Approach to Evaluate the Physiological and Structural Characteristics of the Human Placental Barrier upon Drug Exposure …

FA Elzinga, B Khalili, DJ Touw, JR Prins… - Journal of Clinical …, 2023 - mdpi.com
placenta-on-a-chip has the capacity to recapitulate the key characteristics of the human
placental barrier… an overview of current protocols for developing a placenta-on-a-chip, that …

Microphysiological systems of the placental barrier

N Arumugasaamy, KD Rock, CY Kuo, TL Bale… - Advanced drug delivery …, 2020 - Elsevier
… Although these cell lines represent a cancer cell model, they share key features with human
trophoblasts including their barrier capacity, hormone release, and expression of nutrient …

Modeling of artificial 3D human placenta

R Tutar, B Çelebi-Saltik - Cells tissues organs, 2022 - karger.com
… 3D placenta, placental transfer models as 3D placental barriers… of NPs on the human
placental barrier. The prepared 3D … placental responses such as oxidative stress and barrier

Structure-function correlation in the human placenta: the morphometric diffusing capacity for oxygen at full term.

TM Mayhew, CF Joy, JD Haas - Journal of anatomy, 1984 - ncbi.nlm.nih.gov
… The model recognises that oxygen passing from maternal to fetal erythrocytes must traverse
a total placental barrier comprisingfive main tissue compartments arranged in series. These …

Placental trophoblast-derived factors diminish endothelial barrier function

Y Wang, DF Lewis, Y Gu, Y Zhang… - The Journal of …, 2004 - academic.oup.com
Human placentas were collected from normal and preeclamptic pregnancies in nonsmoking
… the capacity to establish normal junction composition after exposure to these substances. …