Quantitative determination of clopidogrel active metabolite in human plasma by LCMS/MS

M Takahashi, H Pang, K Kawabata, NA Farid… - … of pharmaceutical and …, 2008 - Elsevier
human plasma was developed and validated using liquid chromatography–tandem mass
spectrometry (LCMS/MS… IS were detected in blank human plasma samples, and no significant …

Determination of ambroxol in human plasma using LC-MS/MS

H Kim, JY Yoo, SB Han, HJ Lee, KR Lee - Journal of pharmaceutical and …, 2003 - Elsevier
… in human plasma using liquid chromatography-electrospray ionization tandem mass spectrometry
(LC-ESI/MS/MS)… studies to determine the concentration of ambroxol in human plasma. …

Stereoselective analysis of bupropion and hydroxybupropion in human plasma and urine by LC/MS/MS

R Coles, ED Kharasch - Journal of Chromatography B, 2007 - Elsevier
… Therefore, the purpose of this investigation was to develop and apply a stereoselective
LCMSMS assay for the analysis, in human plasma and urine, of bupropion enantiomers and …

Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations

BK Matuszewski, ML Constanzer… - Analytical …, 1998 - ACS Publications
… of I in human plasma developed in our … ) using LC/MS/MS with a heated nebulizer (HN)
interface. However, to support pharmacokinetic studies following lower oral doses of I to human

Metabolite profiling of a NIST Standard Reference Material for human plasma (SRM 1950): GC-MS, LC-MS, NMR, and clinical laboratory analyses, libraries, and web …

Y Simón-Manso, MS Lowenthal, LE Kilpatrick… - Analytical …, 2013 - ACS Publications
… analysis of a particular SRM for human plasma (SRM 1950). An … Metabolic profiling in
human plasma offers unique … programs to determine the human plasma metabolome (HPM…

LCMS/MS method for the determination of several drugs used in combined cardiovascular therapy in human plasma

O Gonzalez, G Iriarte, E Rico, N Ferreirós… - … of Chromatography B, 2010 - Elsevier
… Although most of these drugs have been individually analyzed in plasma by LC coupled to …
fast LCMS/MS method has been developed for their simultaneous analysis in human plasma

Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma

L Götze, A Hegele, SK Metzelder, H Renz… - Clinica Chimica …, 2012 - Elsevier
BACKGROUND: Increasing numbers of tyrosine kinase inhibitors (TKIs) were studied and
approved for therapy of malignancies and other diseases. The aim of this study was to …

Simultaneous determination of pioglitazone and its two active metabolites in human plasma by LCMS/MS

ZJ Lin, W Ji, D Desai-Krieger, L Shum - Journal of Pharmaceutical and …, 2003 - Elsevier
… Quantitative LCMS/MS methods suitable for the routine … LCMS/MS method for the
simultaneous determination of PIO and its two active metabolites (M-III and M-IV) in human plasma. …

Simultaneous development of six LCMSMS methods for the determination of multiple analytes in human plasma

W Naidong, H Bu, YL Chen, WZ Shou, X Jiang… - … of pharmaceutical and …, 2002 - Elsevier
LCMSMS methods for various types of analytes need to be developed. In this article, we
present the concept of simultaneous development of multiple LCMSMShuman plasma

Determination of pregabalin in human plasma using LC-MS-MS

U Mandal, AK Sarkar, KV Gowda, S Agarwal, A Bose… - Chromatographia, 2008 - Springer
… in human plasma. The analytical method consists in the precipitation of plasma sample with
… by the determination of pregabalin by an LC-MS-MS method using gabapentin as internal …