Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence.
… Abstract Progression to androgen-independent growth of human prostate cancers may be
mediated by alterations in the structure and/or expression of the androgen receptor (AR) gene…
mediated by alterations in the structure and/or expression of the androgen receptor (AR) gene…
LNCaP progression model of human prostate cancer: Androgen‐independence and osseous metastasis
GN Thalmann, RA Sikes, TT Wu, A Degeorges… - … Prostate, 2000 - Wiley Online Library
… human prostate cancer. Evidence suggests that androgen-deprivation may facilitate
androgenindependent progression and acquisition of metastatic potential by prostate cancer cells in …
androgenindependent progression and acquisition of metastatic potential by prostate cancer cells in …
Mechanisms of the development of androgen independence in prostate cancer
… cancer is of … the prostate cancer cell to an androgen independent phenotype is a
complex process that involves selection and outgrowth of pre-existing clones of androgen-independent …
complex process that involves selection and outgrowth of pre-existing clones of androgen-independent …
Molecular alterations during progression of prostate cancer to androgen independence
… in the progression to androgen independence remain largely … mechanisms of androgen
independence in prostate cancer (8… the evolution and progression of prostate cancer, as well as …
independence in prostate cancer (8… the evolution and progression of prostate cancer, as well as …
Prostate cancer: molecular biology of early progression to androgen independence.
MD Sadar, M Hussain… - … -Related Cancer, 1999 - erc.bioscientifica.com
… The androgen-independent regulation of PSA gene … model of human prostate cancer. The
data, as presented in Fig.4, demonstrate the effects of continuous versus intermittent androgen …
data, as presented in Fig.4, demonstrate the effects of continuous versus intermittent androgen …
Transition to androgen-independence in prostate cancer
D Navarro, OP Luzardo, L Fernández, N Chesa… - The Journal of steroid …, 2002 - Elsevier
… Whether these finding operate in human prostatic cancer remain to be demonstrated, but if
so they … the complex cross-talking operating in the hormone resistant prostatic cancer cells. …
so they … the complex cross-talking operating in the hormone resistant prostatic cancer cells. …
Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence
DB Agus, C Cordon-Cardo, W Fox… - … the National Cancer …, 1999 - academic.oup.com
… prostate cancers after androgen withdrawal, we studied cell cycle regulator changes in the
CWR22 human prostate cancer … androgen withdrawal and after the development of androgen …
CWR22 human prostate cancer … androgen withdrawal and after the development of androgen …
The androgen receptor and mechanisms for androgen independence in prostate cancer
J Javidan, AD Deitch, XB Shi… - Cancer …, 2005 - Taylor & Francis
… for Androgen Independent Prostate Cancer Growth Human prostate cancer generally is
sensitive to androgens … , followed by relapse to an androgen-independent state. The molecular …
sensitive to androgens … , followed by relapse to an androgen-independent state. The molecular …
Mechanisms of prostate cancer progression to androgen independence
MJ McPhaul - Best Practice & Research Clinical Endocrinology & …, 2008 - Elsevier
… human prostate cancer and prostate cancer models. Much of this information is consistent with
the androgen … being a central element in prostate cancer development and progression. A …
the androgen … being a central element in prostate cancer development and progression. A …
Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence
ME Taplin, SP Balk - Journal of cellular biochemistry, 2004 - Wiley Online Library
… the cancers are described as androgen-independent or … % of men with androgen-independent
prostate cancer but most … of growth in androgen-independent prostate cancer and that an …
prostate cancer but most … of growth in androgen-independent prostate cancer and that an …
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