… Human serum albumin (HSA) is a globular and monomeric protein in plasma that transport
… We investigated the binding interactions of the Erlotinib Hydrochloride (Erlo) with HSA. Erlo …

… been used to replace human serum albumin in protein- drug … Since the binding ability of
a drug to serum albumin may … , the binding profile of erlotinib hydrochloride to this class of …

… binding of erlotinib hydrochloride (ET), a targeted anticancer drug, to bovine serum albumin
(… Interaction of 4-dimethylaminochalcones with bovine and human serum albumin: A UV–vis …

… Human serum albumin (HSA) is the most abundant plasma protein with a concentration
of ∼630 μM [10]. This protein serves as a transport vehicle for a wide variety of endogenous …

… of erlotinib with HSA using fluorescence UV–Vis and circular dichroism (CD) spectroscopy
to understand the carrier role of serum albumin for such compounds in blood under …

… Typically, BSA was dissolved in distilled water to achieve a 5% (w/v) solution and the pH was
adjusted to 5.0 with HCl. The organic solvent was then added … Structure of serum albumin …

… was obtained by immunizing mice with an antigen conjugated with bovine serum albumin and
3… Erlotinib hydrochloride and O-desmethyl erlotinib were obtained from AdooQ BioScience …

… Erlotinib hydrochloride salt has an equilibrium solubility of approximately 0.4 mg/mL at a pH
of approximately 2 [2,7]. Erlotinib hydrochloride is … of erlotinib and gefitinib in human plasma …

… Therefore, we aim to study BSA interaction with erlotinib as an … Concentration of albumin in
human blood is approximately … bovine serum albumin (BSA) is very similar to human serum …

… The blood plasma is considered to be suitable for the study of physiological activities of metal
ions in human … Erlotinib hydrochloride (ET) with 98% purity was obtained from Shanghai …