Development and validation of LC-MS/MS method for determination of cytisine in human serum and saliva

K Wróblewski, M Szultka-Młyńska, RJ Courtney… - International Journal of …, 2023 - mdpi.com
Cytisine (CYT) is a quinolizidine alkaloid used for nicotine addiction treatment. Recent clinical
trial data regarding cytisine … ) for the determination of CYT in human serum and saliva was …

Comparison of various chromatographic systems for analysis of cytisine in human serum, saliva and pharmaceutical formulation by HPLC with diode array …

K Wróblewski, A Petruczynik, T Tuzimski, D Przygodzka… - Molecules, 2019 - mdpi.com
… The quantitative determination of cytisine in human and animal biological samples has …
for determination of cytisine in pharmaceutical formulation [23]. Analysis of cytisine in human

[PDF][PDF] Applications of cytisine extraction and detection in biological materials for clinical medicine

D Bartusik-Aebisher, D Aebisher… - Acta Poloniae …, 2019 - bibliotekanauki.pl
… and quantification of cytisine in biological fluids such as plasma, serum and urine have … the
quantitative determination of cytisine in biological materials such as organs and human body …

Determination of Cytisine and N-Methylcytisine from Selected Plant Extracts by High-Performance Liquid Chromatography and Comparison of Their Cytotoxic Activity

A Petruczynik, K Wróblewski, J Misiurek, T Plech… - Toxins, 2020 - mdpi.com
… , matrine, and oxymatrine in radix Sophorae tonkinensis extracts were determined … plant
alkaloids including cytisine in a human specimen such as serum or urine were determined on a …

[HTML][HTML] Cytisine induces apoptosis of HepG2 cells

L Yu, X Wang, ZF Chen, B Jiang… - Molecular …, 2017 - spandidos-publications.com
… of cytisine-treated HepG2 cells was examined to determine … effects of cytisine on HepG2
human hepatocellular carcinoma … The results demonstrated that cytisine may inhibit the viability …

Measurements of cadmium levels in relation to tobacco dependence and as a function of cytisine administration

K Wróblewski, J Wojnicka, P Tutka, A Szmagara… - Scientific Reports, 2024 - nature.com
Determination of the correlations between cytisine and Cd concentration Determination of the
correlations between cytisine and … Determination of Cd in saliva was also conducted in the …

Characterization of [3H] cytisine binding to human brain membrane preparations

M Hall, L Zerbe, S Leonard, R Freedman - Brain research, 1993 - Elsevier
… After determining the protein amounts suitable for assay we then examined the rate of …
agreement with our findings using [3H]cytisine in human (ICs0 = 561 nM) and rat (ICs0 = 490 nM). …

Placebo-controlled trial of cytisine for smoking cessation

R West, W Zatonski, M Cedzynska… - … England Journal of …, 2011 - Mass Medical Soc
… This study assessed the efficacy and safety of cytisine as compared with placebo. … study,
cytisine was more effective than placebo for smoking cessation. The lower price of cytisine as …

Cytisine concentration-effect relationships in human smokers

S Jeong - 2015 - researchspace.auckland.ac.nz
cytisine exposure and effect. The main aims of this thesis were therefore: to obtain basic
pharmacokinetic data for cytisine in humans, to study the effects of cytisine … of cytisine in human

Cytisine versus nicotine for smoking cessation

N Walker, C Howe, M Glover… - … England Journal of …, 2014 - Mass Medical Soc
… We investigated whether cytisine was at least as effective as nicotine-replacement therapy …
ratio to receive cytisine for 25 days or nicotine-replacement therapy for 8 weeks. Cytisine was …