Annotation of the human serum metabolome by coupling three liquid chromatography methods to high-resolution mass spectrometry
S Boudah, MF Olivier, S Aros-Calt, L Oliveira… - … of Chromatography B, 2014 - Elsevier
… methods for their coverage of human serum metabolome. … and versatility of liquid
chromatography coupled to high … of the human serum metabolome. To this end, three different …
chromatography coupled to high … of the human serum metabolome. To this end, three different …
[HTML][HTML] The human serum metabolome
N Psychogios, DD Hau, J Peng, AC Guo, R Mandal… - PloS one, 2011 - journals.plos.org
… Overall, it appears that LC-MS or DI-MS methods may be the best choice for serum
metabolomic studies, despite their bias against hydrophilic metabolites. Interestingly, the use of …
metabolomic studies, despite their bias against hydrophilic metabolites. Interestingly, the use of …
[HTML][HTML] Defining blood plasma and serum metabolome by GC-MS
O Kiseleva, I Kurbatov, E Ilgisonis, E Poverennaya - Metabolites, 2021 - mdpi.com
… Metabolomics uses advanced analytical chemistry methods to analyze metabolites in …
of human plasma and serum using mass spectrometry combined with gas chromatography. …
of human plasma and serum using mass spectrometry combined with gas chromatography. …
[HTML][HTML] Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples
M Breier, S Wahl, C Prehn, M Fugmann, U Ferrari… - PloS one, 2014 - journals.plos.org
… targeted metabolomics approach was based on electrospray ionization liquid chromatography…
Based on our data, the optimal method of sample shipment in multicenter trials is to collect …
Based on our data, the optimal method of sample shipment in multicenter trials is to collect …
Analysis of the adult human plasma metabolome
KA Lawton, A Berger, M Mitchell, KE Milgram… - …, 2008 - Taylor & Francis
… Methods: Using gas- and liquid-chromatography … metabolomic results, it is important to
determine the effects of age, sex and race on human plasma metabolites (ie, plasma metabolome…
determine the effects of age, sex and race on human plasma metabolites (ie, plasma metabolome…
Development and performance of a gas chromatography− time-of-flight mass spectrometry analysis for large-scale nontargeted metabolomic studies of human serum
P Begley, S Francis-McIntyre, WB Dunn… - Analytical …, 2009 - ACS Publications
… A method for the preparation and GC−TOF-MS analysis of human serum samples has
been developed and evaluated for application in long-term metabolomic studies. …
been developed and evaluated for application in long-term metabolomic studies. …
Development of a robust and repeatable UPLC− MS method for the long-term metabolomic study of human serum
E Zelena, WB Dunn, D Broadhurst… - Analytical …, 2009 - ACS Publications
… was specifically designed to fulfill the requirements of a long-term metabolomic … of serum
samples from 30 healthy individuals. We also assessed the reproducibility of chromatographic …
samples from 30 healthy individuals. We also assessed the reproducibility of chromatographic …
[HTML][HTML] Molecular phenotyping of a UK population: defining the human serum metabolome
WB Dunn, W Lin, D Broadhurst, P Begley, M Brown… - Metabolomics, 2015 - Springer
… chromatographic MS-based metabolomics study, using samples from over 1,000 individuals,
to provide a comprehensive measurement of their serum metabolomes. … methods able to …
to provide a comprehensive measurement of their serum metabolomes. … methods able to …
… profiling of human serum in lung cancer patients using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry and gas chromatography/mass …
Y Chen, Z Ma, A Li, H Li, B Wang, J Zhong… - Journal of cancer …, 2015 - Springer
… Metabolomic methods have developed rapidly and have become effective tools for disease
… Metabolomic studies in lung cancer patient samples have generally employed techniques …
… Metabolomic studies in lung cancer patient samples have generally employed techniques …
[HTML][HTML] Impact of prolonged blood incubation and extended serum storage at room temperature on the human serum metabolome
B Kamlage, S Neuber, B Bethan… - Metabolites, 2018 - mdpi.com
… blood incubation and extended serum storage at RT on the human serum metabolome using
gas chromatography-… The high sensitivity of modern analytical techniques coupled with the …
gas chromatography-… The high sensitivity of modern analytical techniques coupled with the …
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