… Taken together, we reveal chromatin features in sperm that may contribute to totipotency, …
ageing and lifestyle affects chromatin in a manner that impacts fertility or embryo development. …

… the mammalian sperm cell has important implications for human infertility as … sperm chromatin
structure and function have altered our perception of this highly condensed, inert chromatin…

… and nucleosome occupancy in sperm, we propose that chromatin organization in the male
… , base composition establishes the organization of sperm chromatin and so the regions at …

… nuclei is maintained during sperm condensation by tight … sperm head shape and
chromatin organization inducing sterility speak about manchette importance during chromatin …

… Protamines are the most abundant proteins in the mammalian sperm nucleus (Figure 1)
and their distinctive physicochemical characteristics (such as extreme basicity and high …

… DNA fractions could potentially represent distinct parts of the human genome, we
investigated their overlap further. We found that the two co-exist at more than a quarter of all …

… reason for studying sperm chromatin structure is that the sperm cell is … Therefore, sperm nuclei
provide an excellent model for … -specific arrangement of chromosomes and/ or their distinct …

… DNA in human sperm chromatin is packaged into nucleoprotamine (-85%)and nudeohistone
(-15%). Whether these two chromatin … Sequence-specific packaging would suggest distinct …

… of sperm chromatin, can lead to infertility in humans and potentially transmit aberrant information
to the embryo. One key component of sperm chromatin … to identify distinct differences in …

… a population, our initial observations suggested that this is not true of human spermatozoa
… We believe that those nuclei which exhibit such distinct granularity (PL 3, Fig. and PL 4, Fig. …