[PDF][PDF] The sperm epigenome and potential implications for the developing embryo

TG Jenkins, DT Carrell - Reproduction, 2012 - researchgate.net
… Hammoud SS, Nix DA, Zhang H, Purwar J, Carrell DT & Cairns BR 2009 Distinctive
chromatin in human sperm packages genes for embryo development. Nature 460 473–478. …

[PDF][PDF] Dynamic reorganization of open chromatin underlies diverse transcriptomes during spermatogenesis

S Maezawa, M Yukawa, KG Alavattam… - Nucleic acids …, 2018 - academic.oup.com
… In sperm, we found three classes of promoters dependent on … Thus, we conclude that, from
RS to sperm, open chromatin is … role on sex chromosomes distinct from its role on autosomes (…

Levels of DNA accessibility in human sperm vary across individuals with differing reproductive parameters

ME Gill, M Fischer, C De Geyter, AHFM Peters - bioRxiv, 2024 - biorxiv.org
… Thus it is clear that the packaging of sperm chromatin is distinct and varies between species
and … To examine the chromatin state of sperm we modified the NicE-view assay2426 to label …

Sperm originated chromatin imprints and LincRNAs in organismal development and cancer

S Subhash, M Kanduri, C Kanduri - Iscience, 2020 - cell.com
… , we show that human sperm transcripts are equally important as oocyte. Sperm-specific
and sperm-oocyte common transcripts carry distinct chromatin structures at their promoters …

Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men

SS Hammoud, DA Nix, AO Hammoud… - Human …, 2011 - academic.oup.com
… This study demonstrates differences in the chromatin composition and epigenetic marking
in the sperm of infertile men, especially at imprinted and developmental loci. Although no …

The relationship between chromatin structure and DNA damage in mammalian spermatozoa

K Dominguez, CDR Arca, WS Ward - Sperm chromatin: biological and …, 2011 - Springer
human sperm chromatin structure. We have recently proposed a model for human sperm
chromatinSperm DNA is organized into loop domains of about 50 kb, attached at their bases to …

Recent knowledge concerning mammalian sperm chromatin organization and its potential weaknesses when facing oxidative challenge

A Noblanc, A Kocer, JR Drevet - Basic and clinical andrology, 2014 - Springer
spermatozoa head, complete chromatin remodeling is necessary. This review essentially
focuses on present knowledge of this mammalian sperm … of mammalian sperm chromatin and …

The genomic distribution of histone H3K4me2 in spermatogonia is highly conserved in sperm

R Lambrot, K Siklenka, C Lafleur… - Biology of …, 2019 - academic.oup.com
… During the final stages of sperm formation, chromatin undergoes a long and extensive … by
sperm-specific protamines enabling considerable compaction of chromatin in sperm nuclei [10]…

Unraveling three-dimensional chromatin structural dynamics during spermatogonial differentiation

Y Zheng, L Zhang, L Jin, P Zhang, F Li, M Guo… - Journal of Biological …, 2022 - ASBMB
… Despite the crucial roles of SSCs in maintenance of male fertility, distinct models regarding
the SSC property and cellular hierarchy have been proposed. Specifically, although …

Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis

SS Hammoud, DHP Low, C Yi, DT Carrell, E Guccione… - Cell stem cell, 2014 - cell.com
… were confirmed in human sperm. Here, we reveal AGSC signaling asymmetries and chromatin/…
Thus, our data sets verify the known distinctive differences between Thy1 + and Kit + cells …