Production of biologically active human thioredoxin 1 protein in lettuce chloroplasts

S Lim, H Ashida, R Watanabe, K Inai, YS Kim… - Plant molecular …, 2011 - Springer
… Here, we show that a prospective therapeutic protein, hTrx1, can be expressed in lettuce
chloroplasts and that the lettuce chloroplast-synthesized hTrx1 is biologically active. …

Improvement of vitamin E quality and quantity in tobacco and lettuce by chloroplast genetic engineering

Y Yabuta, H Tanaka, S Yoshimura, A Suzuki… - Transgenic …, 2013 - Springer
… the highest activity in humans. To generate … lettuce plants by chloroplast transformation also
results in an increase in total Toc levels. This is the first report demonstrating that chloroplast

Generation of transplastomic lettuce with enhanced growth and high yield

Y Ichikawa, M Tamoi, H Sakuyama, T Maruta, H Ashida… - GM crops, 2010 - Taylor & Francis
… transplastomic lettuce expressing human thioredoxin 1 (hTrx1)… for human therapies.In this
study, we generated transplastomic … active human thioredoxin 1 protein in lettuce chloroplasts. …

Expression of VGRNb-PE immunotoxin in transplastomic lettuce (Lactuca sativa L.)

M Mirzaee, M Jalali-Javaran, A Moieni, S Zeinali… - Plant molecular …, 2018 - Springer
… In this study, we investigate the expression of VGRNb-PE in transgenic lettuce chloroplasts
and its ability to inhibit the proliferation of VEGFR2-expressing cells in vitro. Our results …

Lettuce (Lactuca sativa L.) leaf-proteome profiles after exposure to cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture: A concentration-dependent …

M Freitas, A Campos, J Azevedo, A Barreiro… - Phytochemistry, 2015 - Elsevier
… , were identified in leaf-lettuce plants exposed to 1 μg/l MC-LR/CYN (chloroplastic 2-Cys
peroxiredoxin BAS1, peroxiredoxin 2, thioredoxin-dependent peroxidase, oxidoreductase, …

Evaluation of lettuce chloroplast and soybean cotyledon as platforms for production of functional bone morphogenetic protein 2

LN Queiroz, FR Maldaner, ÉA Mendes, AR Sousa… - Transgenic …, 2019 - Springer
… attempts to express human BMP2 using two plant systems (lettuce chloroplast and soybean
… introduced in two regions of the lettuce chloroplast genome. Two homoplasmic events were …

The preliminary investigation of chloroplast transformation in lettuce (Lactuca sativa L.).

LCJ Lin ChunJing, WZY Wei ZhengYi… - 2014 - cabidigitallibrary.org
lettuce(Lactuca sativa L.) has been considered by scientists to be an ideal platform for plant
bioreactor. In the present study, 2 lettuce … as explants for chloroplast transformation. To do this…

Stress response of lettuce (Lactuca sativa) to environmental contamination with selected pharmaceuticals: A proteomic study

I Leitão, CC Leclercq, DM Ribeiro, J Renaut… - Journal of …, 2021 - Elsevier
Thioredoxins are present in different organelles (cytosol, mitochondria and chloroplast) using
different substrates and playing a role in defence mechanisms against oxidative stress [88]…

The engineered chloroplast genome just got smarter

S Jin, H Daniell - Trends in plant science, 2015 - cell.com
Chloroplasts are known to sustain life on earth by providing food, fuel, and oxygen through
the process of photosynthesis. However, the chloroplast … genes in chloroplasts. These tools …

The chloroplasts as platform for recombinant proteins production

N Scotti, M Bellucci, T Cardi - Translation in mitochondria and other …, 2013 - Springer
… in tobacco and lettuce chloroplasts. CTB-AMA1 and CTB-MSP1 were accumulated up to
13.2 % and 10.1 % TSP in transplastomic tobacco plants and up to 7.3 % and 6.1 % TSP in …