The interaction of gallium with biological systems

RL Hayes - International Journal of Nuclear Medicine and Biology, 1983 - Elsevier
… Our studies on the effect of scandium on the tissue distribution of “‘Ga provides an
interesting example of the hazards involved in … animals to humans. We found that adminis- …

The natural concentration of gallium in human tissues

HH Lange - Nuklearmedizin-NuclearMedicine, 1973 - thieme-connect.com
… differences between the healthy individual and the cancer patient as to the Ga distribution. …
human tissue, neither in mammary tissue, liver tissue, nor plasma. The established gallium

Mechanisms of localization of gallium-67 in tumors

SM Larson - Seminars in nuclear medicine, 1978 - Elsevier
gallium concentrates in tumor, but if too much stable gallium … free ~TGa uptake in human
tissues is seen after intravenous … CL: Distribution of gallium in human tissues after intravenous …

Mechanisms of therapeutic activity for gallium

LR Bernstein - Pharmacological reviews, 1998 - ASPET
… vivo studies of gallium tissue distribution have used trace quantities of radioactive gallium,
the … entirely consistent, all Ga tissue distribution studies find that Ga concentrates at the same …

[PDF][PDF] Preclinical toxicology and tissue gallium distribution of a novel antitumour gallium compound: tris (8-quinolinolato) gallium (III).

P Collery, JL Domingo, BK Keppler - cancer, 1996 - researchgate.net
… Although this agent has a better bioavailability after oral administration than Ga chloride, it …
, and to determine tissue Ga distribution in healthy Swiss mice. Ga assays were performed by …

[PDF][PDF] Mechanism of gallium-67 accumulation in tumors

MF Tsan, U Scheffel - Journal of nuclear medicine, 1986 - Soc Nuclear Med
… Hayes RL: The tissue distribution of gallium radio nuclides. J NuciMed 18:740—741,1977
28. English D, Clairoux-Moreau 5, McPherson TA: Up take ofGa-67 citrate by physiologically-…

[PDF][PDF] The intestinal absorption and tissue distribution of aluminium, gallium and scandium: a comparative study

G FARRAR, ANNP MORTON, JA BLAIR - 1987 - researchgate.net
… Of the aluminium and gallium taken up by the tissue approximately 170 is transported to the
… less than that of gallium and aluminium. Tissue distribution of orally administered aluminium, …

Gallium in cancer treatment

P Collery, B Keppler, C Madoulet, B Desoize - Critical reviews in oncology …, 2002 - Elsevier
… A modification of cell cycle distribution is observed after at least 24 h incubation with Ga: the
… that careful monitoring of fibrosis in all patient tissues during treatment with Ga is justified. …

… of an investigational anticancer gallium (III) drug: interaction with serum proteins, elemental distribution pattern, and coordination of the compound in tissue

AA Hummer, C Bartel, VB Arion… - Journal of Medicinal …, 2012 - ACS Publications
… of gallium(III) in mouse tissue are the main targets in this study. … of Ga with the Zn distribution
in tumor tissue. In the liver sample the Ga concentration was correlated to the Fe distribution

Gallium‐67 distribution in pregnant mammals

RL Tyndall, SJ Chaskes, JE Carlton… - Journal of …, 1976 - Wiley Online Library
… is markedly reduced in tumor-bearing rats (Hayes, '75, personal communication) we
examined the localization of "Ga in thymus tissue of pregnant rats. Unlike gel filtration of normal …