Regulatory T cells in cancer
M Beyer, JL Schultze - Blood, 2006 - ashpublications.org
… numbers of regulatory T cells (T reg cells) in solid tumors and … Whereas the biology of CD4
+ CD25 + FOXP3 + T reg cells in … human tumors were mainly focused on CD4 + CD25 + T reg …
+ CD25 + FOXP3 + T reg cells in … human tumors were mainly focused on CD4 + CD25 + T reg …
FOXP3 defines regulatory T cells in human tumor and autoimmune disease
I Kryczek, R Liu, G Wang, K Wu, X Shu, W Szeliga… - Cancer research, 2009 - AACR
… T cells may express FOXP3. It is thought that FOXP3 is not a specific marker to determine
regulatory T cells (Treg) in humans. … FOXP3 + T cells, primary FOXP3 + and FOXP3 - T cells in …
regulatory T cells (Treg) in humans. … FOXP3 + T cells, primary FOXP3 + and FOXP3 - T cells in …
BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors
…, T Irie, J Yuda, S Kumagai, T Tanegashima… - Science …, 2022 - science.org
… tumor microenvironment (TME). Here, we showed that T reg cells in the TME of human lung
cancers … compared with CD8 + T cells, conventional CD4 + T cells in the TME, and peripheral …
cancers … compared with CD8 + T cells, conventional CD4 + T cells in the TME, and peripheral …
Tim-3 expression defines regulatory T cells in human tumors
… Tim-3 + CD4 T cells accumulate in human tumor tissues, and that Tim-3 … regulatory T cells
(Tregs) in several types of human tumors. Tim-3 + Tregs from human hepatocellular carcinoma …
(Tregs) in several types of human tumors. Tim-3 + Tregs from human hepatocellular carcinoma …
Targeting regulatory T cells in tumors
C Liu, CJ Workman, DAA Vignali - The FEBS journal, 2016 - Wiley Online Library
… T reg cells have been shown to infiltrate human tumors and are thought to limit antitumor …
human ovarian cancer patients revealed that elevated frequencies of T reg cells at the tumor …
human ovarian cancer patients revealed that elevated frequencies of T reg cells at the tumor …
Regulatory T cells and human disease
S Sakaguchi, N Mikami, JB Wing… - Annual review of …, 2020 - annualreviews.org
… Naturally occurring CD4 + regulatory T cells (Tregs) are an … and 1980s suggesting the
existence of T cells capable of suppressing … Proteomic analyses of human regulatory T cells reveal …
existence of T cells capable of suppressing … Proteomic analyses of human regulatory T cells reveal …
Regulatory T cells exhibit distinct features in human breast cancer
G Plitas, C Konopacki, K Wu, PD Bos, M Morrow… - Immunity, 2016 - cell.com
… of T cell subsets-resident in primary human breast tumors, we evaluated tissue-resident
lymphocytes from tumors, NBP, and lymphocytes … that the T cell composition in the human tumor …
lymphocytes from tumors, NBP, and lymphocytes … that the T cell composition in the human tumor …
Regulatory T cells in tumor immunity
H Nishikawa, S Sakaguchi - International journal of cancer, 2010 - Wiley Online Library
… tumor immunity.4 Among key mechanisms of self-tolerance, recent studies have shown that
regulatory T cells (… nonself, as well as quasi-self tumor antigens.5, 6 The most physiologically …
regulatory T cells (… nonself, as well as quasi-self tumor antigens.5, 6 The most physiologically …
Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
HY Wang, DA Lee, G Peng, Z Guo, Y Li, Y Kiniwa… - Immunity, 2004 - cell.com
… + T cell lines that recognized an autologous tumor cell line (M102) generated from the same
tumor … A testicular antigen aberrantly expressed in human cancers detected by autologous …
tumor … A testicular antigen aberrantly expressed in human cancers detected by autologous …
Regulatory T cells and cancer
HY Wang, RF Wang - Current opinion in immunology, 2007 - Elsevier
… cells in the total T cell population isolated from tumor tissues or peripheral blood in a variety
of cancers, … In general, Treg cells identified from most human cancers are of the CD4 + CD25 …
of cancers, … In general, Treg cells identified from most human cancers are of the CD4 + CD25 …
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