… Parkinson’s disease (PD), and the inability to walk, talk, and think, Huntington’s disease (HD…
as a central feature of brain degenerative diseases. Oxidative stress, a condition that occurs …

… , who provided a classic account of the condition in 1872, Huntington's disease (HD), is a …
Oxygen free radicals, frequently referred to as reactive oxygen species (ROS), are normally …

Huntington's disease (HD), an inherited neurodegenerative disorder, results from an abnormal
polyglutamine extension in the N-terminal region of the huntingtin protein. This mutation …

… The formation of reactive oxygen species (ROS) and the … of mice transgenic for the Huntington’s
disease (HD) mutation. … transgenic animals to generate oxygen radicals as a response …

… Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder
… strategies that reduce reactive oxygen species may ameliorate the neurodegenerative …

… However, no evidence of ER-mitochondria contact alterations have been demonstrated
in Huntington's diseases (HD). HD is an autosomal dominant neurodegenerative disorder …

… They also released elevated levels of reactive oxygen species that have neurotoxic potential.
Accompanying such phenotypes, human Huntington’s disease PSC-derived microglia …

Huntington’s disease (HD) as an inherited neurodegenerative disorder leads to neuronal
loss in striatum. Progressive motor dysfunction, cognitive decline, and psychiatric disturbance …

It has been five years since the elucidation of the genetic mutation underlying the pathogenesis
of Huntington's disease (HD) (97), however the precise mechanism of the selective …

… calcium and elevated intracellular iron may interact to result in elevated levels of reactive
oxygen species leading to lipid peroxidation, DNA damage, and neuronal cell death. …