过去一年中添加的文章,按日期排序

Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK

M Korenjak, NA Temiz, SA Keita, B Chavanel… - bioRxiv, 2024 - biorxiv.org
26 天前 - … ) and other polycyclic aromatic hydrocarbons (PAH) have … Next, we carried out
targeted DNA adduct analyses of … confirm the formation of POB DNA adducts under the exposure …

BaP/BPDE exposure causes human trophoblast cell dysfunctions and induces miscarriage by up-regulating lnc-HZ06-regulated IL1B

J Guo, J Zhao, P Tian, Z Xu, R Wang, W Chen… - Journal of Hazardous …, 2024 - Elsevier
43 天前 - … of polycyclic aromatic hydrocarbons, and its ultimate … -DNA adducts were significantly
higher in RM vs HC villous tissues. Then, we divided the levels of BPDE-DNA adducts into …

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility

Y Xiao, Y Shen, H Song, F Gao, Z Mao, Q Lv, C Qin… - Archives of …, 2024 - Springer
90 天前 - … pathways of polycyclic aromatic hydrocarbons and tobacco-… DNA adducts and
reactive oxygen species (ROS) formation (Shimada 2006). DNA damage caused by DNA adducts

Particulate polycyclic aromatic hydrocarbons and metals, DNA methylation and DNA methyltransferase among middle-school students in China

W Gu, T Wang, Y Lin, Y Wang, Y Chen, Y Dai… - Science of The Total …, 2024 - Elsevier
116 天前 - … Our results showed that BPDE-albumin adduct and urinary Cd significantly decrease
in DNMT1 and DNMT3A gene expression. However, the mediating effect analysis did not …

Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Induced Carcinogenesis and Tumorigenesis by Omega-3 Fatty Acids in Mice In Vivo

G Xia, G Zhou, W Jiang, C Chu, L Wang… - International Journal of …, 2024 - mdpi.com
118 天前 - … EPA and DHA decreased PAH-DNA adduct formation in the lungs and livers of mice
by 30–45%. We also found that this attenuation of DNA adduct formation by EPA/DHA was, …

XRCC1 Polymorphisms p.Arg194Trp, p.Arg280His, and p.Arg399Gln, Polycyclic Aromatic Hydrocarbons, and Infertility: A Case–Control and In Silico Study

JS Sahota, K Guleria, V Sambyal - Biochemical Genetics, 2024 - Springer
125 天前 - … its ability to efficiently repair DNA damage. Polycyclic aromatic hydrocarbons or
PAHs are genotoxic compounds which form bulky DNA adducts that are linked with infertility. …

Reactions of deoxyribonucleotide bases with sulfooxymethyl or halomethyl polycyclic aromatic hydrocarbons induce unwinding of DNA supercoils

AF Lehner - Toxicology Mechanisms and Methods, 2024 - Taylor & Francis
215 天前 - … Relating aromatic hydrocarbon-induced DNA adducts and cH-ras mutations in
mouse skin papillomas: the role of apurinic sites. Proceedings of the National Academy of …

AHR-mediated DNA damage contributes to BaP-induced cardiac malformations in zebrafish

H Zou, M Zhang, J Chen, S Aniagu, Y Jiang… - Science of the Total …, 2024 - Elsevier
291 天前 - hydrocarbon widely present in the environment. We previously reported that the aryl
hydrocarbon … exposure significantly increased BPDE-DNA adducts, mitochondrial damage, …

[PDF][PDF] Mechanisms of chemical-induced degeneration of monoaminergic neurons

AAMI Fergany - 2023 - tus.repo.nii.ac.jp
328 天前 - … in rice, aromatic hydrocarbon quinones formed during … cysteine residues, forming
adducts and activating cellular … acid (DNA) molecules to form DNA adducts, inhibit the …

Regulation of Xenobiotic-Metabolizing Enzymes by 5-Demethylnobiletin and Nobiletin to Mitigate Benzo[a]pyrene-Induced DNA Damage In Vitro and In Vivo

WS Lin, WC Cheng, PY Ho, CT Ho… - Journal of agricultural …, 2023 - ACS Publications
336 天前 - … polycyclic aromatic hydrocarbon that is metabolized by cytochrome P450 family 1
enzymes (CYP 1s) and can bind to DNA to form DNA adducts, leading to DNA damage and …