Injectable hydrogel-based drug delivery system for cartilage regeneration

L García-Fernández, M Olmeda-Lozano… - Materials Science and …, 2020 - Elsevier
… In this work, we developed an injectable semi-IPN hydrogel based on gelatin and … The
application of a semi-IPN hydrogel system able to in situ release HA to the injured cartilage would …

Spatiotemporal regulation of endogenous MSCs using a functional injectable hydrogel system for cartilage regeneration

Y Dong, Y Liu, Y Chen, X Sun, L Zhang, Z Zhang… - NPG Asia …, 2021 - nature.com
hydrogel system was designed to recruit endogenous stem cells and induce their differentiation
into chondrocytes. The system … to form an injectable hydrogel, which showed sequential …

Advances of injectable hydrogel-based scaffolds for cartilage regeneration

J Li, G Chen, X Xu, P Abdou, Q Jiang… - Regenerative …, 2019 - academic.oup.com
… for hydrogels in cartilage regeneration. However, networks of traditional hydrogels are …
which are inferior to those of natural cartilage [10]. To enhance the mechanical properties of …

Hydrogel based cartilaginous tissue regeneration: recent insights and technologies

YJ Chuah, Y Peck, JEJ Lau, HT Hee, DA Wang - Biomaterials science, 2017 - pubs.rsc.org
… (Cartilage Regeneration System) which is a novel rat tail tendon type I collagen hydrogel
occupied by autologous chondrocytes. The three-dimension collagen hydrogel provides a …

[HTML][HTML] Natural hydrogels for cartilage regeneration: Modification, preparation and application

L Li, F Yu, L Zheng, R Wang, W Yan, Z Wang… - Journal of orthopaedic …, 2019 - Elsevier
… This review introduces the natural hydrogels that are often used in cartilage tissue …
putative challenges and directions for the use of natural hydrogels in cartilage regeneration. …

Dual growth factor-releasing nanoparticle/hydrogel system for cartilage tissue engineering

SM Lim, SH Oh, HH Lee, SH Yuk, GI Im… - Journal of Materials …, 2010 - Springer
… nanoparticle/hydrogel system (refer to Fig. 5), we can recognize that the nanoparticle/hydrogel
system may provide desirable growth factor delivery kinetics for cartilage regeneration, as …

Dual delivery of TGF-β3 and ghrelin in microsphere/hydrogel systems for cartilage regeneration

J Lin, L Wang, J Lin, Q Liu - Molecules, 2021 - mdpi.com
… a microsphere/hydrogel system that provides two growth factors that promote cartilage
repair: transforming growth factor-β3 (TGF-β3) to enhance cartilage tissue formation and ghrelin …

A chondroitin sulfate based injectable hydrogel for delivery of stem cells in cartilage regeneration

X Li, Q Xu, M Johnson, X Wang, J Lyu, Y Li… - Biomaterials …, 2021 - pubs.rsc.org
… To customise a scaffold in favour to support cartilage regeneration, we selected a … PEG
due to the existence of CS in the natural cartilage and beneficial biological properties. …

Injectable hydrogels and nanocomposite hydrogels for cartilage regeneration

O Jeznach, D Kołbuk… - Journal of Biomedical …, 2018 - Wiley Online Library
… interest in the tissue engineering approach to cartilage repair. This review discusses the …
emphasis on hydrogels in cartilage tissue engineering. We highlight injectable hydrogels with …

[HTML][HTML] Advanced hydrogels for the repair of cartilage defects and regeneration

W Wei, Y Ma, X Yao, W Zhou, X Wang, C Li, J Lin… - Bioactive materials, 2021 - Elsevier
… For the design of hydrogels aiming at cartilage regeneration and clinical translation, we
summarized some criteria as well as suggestions for optimized outcomes. 1) Biocompatibility: …