… mediators of cell and tissue damage, others have been shown to be crucial for cell survival
… as a major second messenger in redox signaling is hydrogen peroxide (H 2 O 2 ). This small…

… Hydrogen peroxide (H2O2) is an incompletely reduced metabolite of oxygen … living cells
depending on the extent, timing, and location of its production. Characterization of the cellular …

… We next assessed the ability of PF1 to operate within living cells. HEK cells were incubated
with 5 μM PF1 for 5 min at 25 C and show negligible intracellular background fluorescence (…

… moiety for detection of hydrogen peroxide localized to cellular mitochondria. Confocal … cell
types show that MitoPY1 can visualize localized changes in mitochondrial hydrogen peroxide …

Described here is a localized H 2 O 2 generation‐detection system consisting of a yeast D‐amino
acid oxidase (DAAO) and two spectrally distinct variants of biosensor, HyPer2 and …

… peroxide. Two-photon confocal microscopy experiments in live macrophages show that PL1
can ratiometrically visualize localized hydrogen peroxide bursts generated in living cells at …

… of live biological specimens and responds to local fluxes of hydrogen peroxide (H 2 O 2 ) by
… MitoPY1 can be used to measure mitochondrial H 2 O 2 levels in both cell culture and tissue …

… targets the mitochondria in living cells and is sensitive to … living cells, and the fluorescence
colocalization studies indicate that the probe localizes solely in the mitochondria of HeLa cells…

… selectively imaging hydrogen peroxide (H 2 O 2 ) generated at physiological cell signaling
… during the phagocytic respiratory burst and A431 cells in response to EGF stimulation. We …

… in live cells and have become indispensable tools in cell … quantify calcium concentrations
in cells. Following the same … ) that can quantify GSH concentrations in live cells, (2) along with …