… and safety of hypoxia-inducible factor prolyl hydroxylase inhibitors in patients with chronic kidney disease: meta-analysis of phase 3 randomized controlled trials
R Minutolo, ME Liberti, V Simeon… - Clinical Kidney …, 2024 - academic.oup.com
… Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are new therapeutic
agents for … We selected phase 3 randomized clinical trials (RCTs) comparing HIF-PHIs and …
agents for … We selected phase 3 randomized clinical trials (RCTs) comparing HIF-PHIs and …
Effect of hypoxia-inducible factor-prolyl hydroxylase inhibitors on anemia in patients with CKD: a meta-analysis of randomized controlled trials including 2804 patients
B Wang, Q Yin, YC Han, M Wu, ZL Li, Y Tu, L Zhou… - Renal failure, 2020 - Taylor & Francis
… all clinical trials (confined to phase II or III) about HIF-PHIs on anemia treatment. Hence, we
first conducted a meta-analysis of randomized controlled trials (… randomized controlled trials …
first conducted a meta-analysis of randomized controlled trials (… randomized controlled trials …
[HTML][HTML] Hypoxia-inducible factor prolyl hydroxylase inhibitors: a potential new treatment for anemia in patients with CKD
N Gupta, JB Wish - American Journal of Kidney Diseases, 2017 - Elsevier
… yet to be proved in long-term clinical trials. One significant concern … clinical trials in the
United States; this report provides a focused review of HIF-PH inhibitors and their potential clinical …
United States; this report provides a focused review of HIF-PH inhibitors and their potential clinical …
[HTML][HTML] Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease
M Sugahara, T Tanaka, M Nangaku - Kidney international, 2017 - Elsevier
… randomized controlled studies have demonstrated that the use of ESAs with a target
hemoglobin level of >13 g/dl has been associated with an increased rate of cardiovascular events …
hemoglobin level of >13 g/dl has been associated with an increased rate of cardiovascular events …
… inducible factor-prolyl hydroxylase inhibitors in anemic patients with non-dialysis dependent chronic kidney disease: a meta-analysis of randomized clinical trials
… We conducted a meta-analysis of randomized clinical trials to assess the efficacy and safety
of HIF-PHI in non-dialysis-dependent CKD patients. Primary outcome was hemoglobin (Hb) …
of HIF-PHI in non-dialysis-dependent CKD patients. Primary outcome was hemoglobin (Hb) …
Effects of hypoxia-inducible factor prolyl hydroxylase inhibitors on iron regulation in non-dialysis-dependent chronic kidney disease patients with anemia: a systematic …
J Li, QH Xie, L You, NX Xu, CM Hao - Pharmacological Research, 2021 - Elsevier
… showed that hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) … among clinical
trials. We performed a systematic review and meta-analysis of randomized controlled trials …
trials. We performed a systematic review and meta-analysis of randomized controlled trials …
Long‐term efficacy and safety of hypoxia‐inducible factor prolyl hydroxylase inhibitors in anaemia of chronic kidney disease: A meta‐analysis including 13,146 …
H Chen, Q Cheng, J Wang, X Zhao… - Journal of clinical …, 2021 - Wiley Online Library
… Randomized controlled trials comparing treatment with HIF-PHD inhibitors versus placebo …
and international clinical trial registries. Meta-analysis was performed on main outcomes with …
and international clinical trial registries. Meta-analysis was performed on main outcomes with …
Four-week studies of oral hypoxia-inducible factor–prolyl hydroxylase inhibitor GSK1278863 for treatment of anemia
L Holdstock, AM Meadowcroft, R Maier… - Journal of the …, 2016 - journals.lww.com
… For the final data set and for all analyses (including hemoglobin), blood was sent to Quest
Diagnostic Clinical Trials for analysis. Other laboratory tests were also analyzed centrally by …
Diagnostic Clinical Trials for analysis. Other laboratory tests were also analyzed centrally by …
A Prospective Randomized Controlled Clinical Study to Investigate the Efficacy and Safety of Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitors in Non-Dialysis …
A Sezai, M Abe, T Maruyama, M Taoka… - Journal of Clinical …, 2024 - mdpi.com
… We performed a prospective, randomized, controlled study to … types of HIF-PH inhibitors.
The primary endpoint was a … the first head-to-head comparative study of HIF-PH inhibitors. …
The primary endpoint was a … the first head-to-head comparative study of HIF-PH inhibitors. …
Hypoxia-inducible factor prolyl hydroxylase inhibitors in patients with renal anemia: a meta-analysis of randomized trials
T Wen, X Zhang, Z Wang, R Zhou - Nephron, 2020 - karger.com
… Background: Hypoxia-inducible factor prolyl hydroxylase inhibitors (… randomized controlled
trials (RCTs). Information about efficacy and safety was extracted and combined using random…
trials (RCTs). Information about efficacy and safety was extracted and combined using random…
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