Hypermethylation of the hMLH1 Gene Promoter in Human Gastric Cancers with Microsatellite Instability
AS Fleisher, M Esteller, S Wang, G Tamura, H Suzuki… - Cancer research, 1999 - AACR
… This hypermethylation has been associated with hMLH1 … hMLH1 gene inactivation and
MMR deficiency. Therefore, we studied the prevalence of hMLH1 promoter hypermethylation in a …
MMR deficiency. Therefore, we studied the prevalence of hMLH1 promoter hypermethylation in a …
Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia
AS Fleisher, M Esteller, G Tamura, A Rashid, OC Stine… - Oncogene, 2001 - nature.com
… repair gene promoter and diminished hMLH1 … hMLH1 hypermethylation has not been
studied in early gastric neoplasms. We therefore investigated hMLH1 hypermethylation, hMLH1 …
studied in early gastric neoplasms. We therefore investigated hMLH1 hypermethylation, hMLH1 …
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
… methylation. To address these questions, we have analyzed hMLH1 promoter methylation
in several subtypes of CRC, including those with known mutations of MMR genes. We have …
in several subtypes of CRC, including those with known mutations of MMR genes. We have …
Hypermethylation of the hMLH1 Promoter in Colon Cancer with Microsatellite Instability
JM Cunningham, ER Christensen, DJ Tester, CY Kim… - Cancer research, 1998 - AACR
… , we have examined the methylation status of the pre sumptive hMLHl promoter region in 31
… hMLHl protein expression (MLH- or MLH+), and their gene mutation (Mut+ or Mut-) status. …
… hMLHl protein expression (MLH- or MLH+), and their gene mutation (Mut+ or Mut-) status. …
[HTML][HTML] hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
M Esteller, L Catasus, X Matias-Guiu, GL Mutter… - The American journal of …, 1999 - Elsevier
… between hMLH1 promoter hypermethylation, loss of hMLH1 … involvement of aberrant
methylation of hMLH1 in UEC with … genes, and we show that hMLH1 promoter hypermethylation …
methylation of hMLH1 in UEC with … genes, and we show that hMLH1 promoter hypermethylation …
Promoter hypermethylation: an important epigenetic mechanism for hMLH1 gene inactivation in head and neck squamous cell carcinoma
K Liu, H Huang, P Mukunyadzi, JY Suen… - … -Head and Neck Surgery, 2002 - Elsevier
… mutations in hMLH1 in sporadic … hMLH1 gene in association with promoter hypermethylation.
It has been documented that hypermethylation of the hMLH1 gene promoter causes gene …
It has been documented that hypermethylation of the hMLH1 gene promoter causes gene …
[HTML][HTML] Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer
HM Nan, YJ Song, HY Yun, JS Park… - World journal of …, 2005 - ncbi.nlm.nih.gov
… hypermethylation of the hMLH1 gene promoter … hypermethylation of the hMLH1 gene
promoter and environmental factors, genetic polymorphisms of major metabolic enzymes, genetic …
promoter and environmental factors, genetic polymorphisms of major metabolic enzymes, genetic …
[HTML][HTML] Hypermethylation of the hMLH1 gene promoter in solitary and multiple gastric cancers with microsatellite instability
K Sakata, G Tamura, Y Endoh, K Ohmura… - British journal of …, 2002 - nature.com
… frequent hypermethylation of the hMLH1 gene promoter in … cancers with MSI-H, methylated
alleles were rarely detected in … that hypermethylation of the hMLH1 gene promoter occurs in …
alleles were rarely detected in … that hypermethylation of the hMLH1 gene promoter occurs in …
Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression
G Deng, A Chen, E Pong, YS Kim - Oncogene, 2001 - nature.com
… luciferase gene in the plasmids can also be methylated by … methylation of hMLH1 promoter
from that by the methylation of … carries a short proximal promoter sequence without HhaI or …
from that by the methylation of … carries a short proximal promoter sequence without HhaI or …
Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma
K Liu, C Zuo, QK Luo, JY Suen, E Hanna… - Diagnostic Molecular …, 2003 - journals.lww.com
… appears to be primarily involved in the inactivation of the hMLH1 gene in sporadic form of …
HNSCC for hMLH1 protein expression and promoter hypermethylation by IHC and methylation-…
HNSCC for hMLH1 protein expression and promoter hypermethylation by IHC and methylation-…