… lung pathology demonstrated the potential of this new tool for capturing the features of lung
gas-flow … be achieved routinely using hyperpolarized noble gases. This dramatic increase in …

… from which one could then obtain a quantitative measure of gas flow over time. Figure 8
shows the local variation of the signal in … Human lung air spaces: potential for MR imaging with …

… Helium-3 gas for our MRI experiments was hyperpolarized with two home… flow of the
back-pressuring ordinary helium gas regulates the pressure and flow of the hyperpolarized 3 He gas…

… The flow of HP gas was … Noble gas diffusion in the guinea pig lung was measured in Part
I of this series (17), demonstrating evidence of restricted diffusion in the distal pulmonary gas …

… , we compared respiratory gas samples … gas and respiratory gas distribution and mixing
may differ, however, if transitions to turbulent flow occur in different regions for 3 He and the air-O …

… Bronchi and airspaces where gas is unable to flow until … values from conventional respiratory
gas analysis, which serves … 3 He MRI after inhalation of hyperpolarized 3He gas reveals a …

… ) and expiration (EXPIR) gas flows and ports to control the supply of normal breathing …
results with 3He/O2 mixtures,1 indicating that 3He spin-lattice relaxation in the lung gas space is …

… imaging with hyperpolarized 3He gas has the potential to show the acinar units of the lungs
(28), … of blood flow and perfusion in the lungs and the heart. Further, combined imaging of the …

… ability to measure multiple pulmonary functional biomarkers. … translation of hyperpolarized
gas imaging to the pulmonary clinic … of gas flow, appear as dark regions in hyperpolarized gas …

… Given the high signal available from hyperpolarized noble gases, this method also … -time,
the pulmonary gas-flow dynamics. An initial attempt to image gas dynamics in the human lung, …