Lacidipine has antiatherosclerotic effects independent of its actions on lipid metabolism and blood pressure

GY Anacak, L Üstünes, OY Dilsiz, A Ergul - Vascular pharmacology, 2010 - Elsevier
… on cholesterol levels, lipid metabolism or oxidant stress … lacidipine is protective of intimal
thickening and vascular dysfunction in early atherosclerosis in the absence of the hypertension

Effect of lacidipine, a long-acting calcium antagonist, on hypertension and lipids: a 1 year follow-up

S Soro, LA Ferrara - European journal of clinical pharmacology, 1991 - Springer
… The results of the present study show that lacidipine, a dihydropyridine calcium antagonist,
was an effective antihypertensive drug, and that it was devoid of untoward effects on lipid

Lacidipine: a review of its use in the management of hypertension

PL McCormack, AJ Wagstaff - Drugs, 2003 - Springer
… in the accumulation of lacidipine in membrane lipid bilayers from … Lacidipine has natriuretic
and diuretic effects and is metabolically neutral, having no adverse effects on glucose or lipid

Endothelial dysfunction, hypertension and atherosclerosis: a review of the effects of lacidipine

H Haller, F Cosentino, TF Lüscher - Drugs in R & D, 2002 - Springer
… [31] In addition, lacidipine does not exert negative effects on blood lipid levels. Under
conditions of high serum cholesterol levels in animals, lacidipine has demonstrated greater activity …

[PDF][PDF] Beneficial effects of combined therapy with lacidipine and candesartan in obese hypertensive patients

T Ashcheulova, N Gerasimchuk, O Kovalyova… - Romanian Journal of …, 2018 - sciendo.com
… During the course of treatment with combination of lacidipine and candesartan in hypertensive
patients with overweight and … on carbohydrate and lipid profili. Ukrainian Therapeutical J. …

Effects of lacidipine on vascular responses in patients with coronary artery disease

JH Bae, E Bassenge, DM Lim, YC Synn, KY Kim… - International journal of …, 2005 - Elsevier
lipid level or the changes of blood pressure (Fig. 2). This means that the effects of lacidipine
on common carotid IMT regression was not related with its blood pressure-lowering effects. …

Clinical position of lacidipine, a new dihydropyridine calcium antagonist, in the treatment of hypertension

G Leonetti - Journal of cardiovascular pharmacology, 1991 - journals.lww.com
… Furthermore, lacidipine, like nifedipine, was able to reverse the early changes … blood
pressure elevation. Although we are missing the most important data, that is the effect of lacidipine

Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension

C Rhoda Lee, HM Bryson - Drugs, 1994 - Springer
… a long duration of action. In studies using ambulatory blood pressure monitoring, lacidipine
2 to 8mg administered once daily in the morning reduced blood pressure over 24 hours with …

Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients

S Taddei, A Virdis, L Ghiadoni, S Uleri, A Magagna… - …, 1997 - Am Heart Assoc
… Furthermore, body weight, lipid profile, and glucose … the effect of lacidipine, a dihydropyridine
calcium-entry blocker, on endothelium-dependent vasodilation in essential hypertensive

Changes in iNOS activity, oxidative stress and melatonin levels in hypertensive patients treated with lacidipine

G Escames, H Khaldy, J León, L González… - … of hypertension, 2004 - journals.lww.com
… oxide synthase (iNOS) activity, plasma levels of nitrite, lipid peroxidation (LPO) and melatonin
in human essential hypertension before and 6 months after 4 mg/day lacidipine treatment. …