A single exposure to particulate or gaseous air pollution increases the risk of aconitine-induced cardiac arrhythmia in hypertensive rats

MS Hazari, N Haykal-Coates, DW Winsett… - Toxicological …, 2009 - academic.oup.com
… emissions, on arrhythmogenicity in normotensive and hypertensive rats; and (3) determine
if … arrhythmia in hypertensive rats. We hypothesized that inhaled air pollutants sensitize the …

Particulate matter, air pollution, and blood pressure

RD Brook, S Rajagopalan - … of the American Society of Hypertension, 2009 - Elsevier
air pollution mixture are important issues to further elucidate. Nonetheless, given the omnipresent
nature of both air pollution and hypertension … studies with hypertensive rats found the …

Exposure to atmospheric pollutants is associated with alterations of gut microbiota in spontaneously hypertensive rats

D Chen, C Xiao, H Jin, B Yang… - Experimental and …, 2019 - spandidos-publications.com
… In conclusion, herein the effects of air pollutants on the gut microbiota of SHR rats are
reported. Moreover, statistically significant changes in the microbiota were investigated. Changes …

Direct and acute cardiotoxic effects of ultrafine air pollutants in spontaneously hypertensive rats and Wistar—Kyoto rats

H Hwang, RA Kloner, MT Kleinman… - Journal of …, 2008 - journals.sagepub.com
… also act as carriers for other toxic components of air pollution. In addition, a small fraction of
… -perfused hearts isolated from normal healthy rats.Hypertension is highly prevalent in the …

Rat models of cardiometabolic diseases: baseline clinical chemistries, and rationale for their use in examining air pollution health effects

UP Kodavanti, JC Russell, DL Costa - Inhalation Toxicology, 2015 - Taylor & Francis
… FHH rats have not been employed as a susceptible model of hypertension in any air pollution
… It is likely that the response to air pollution will be different between hypertensive SH and …

The spontaneously hypertensive rat as a model of human cardiovascular disease: evidence of exacerbated cardiopulmonary injury and oxidative stress from inhaled …

UP Kodavanti, MC Schladweiler, AD Ledbetter… - Toxicology and applied …, 2000 - Elsevier
… and mortality from particulate matter (PM) air pollution at levels much lower than would be
found in … susceptibility of either organ to the effects of air pollution; however, through the use of …

Enhanced cerebral microbleeds by long-term air pollution exposure in spontaneously hypertensive rats

L Cai, J Yang, E Cosky, R Xin, X Geng… - Neurological …, 2022 - Taylor & Francis
hypertensive rats (SHR) and eight Wistar-Kyoto (WKY) rats were exposed to either filtered
air … the relationship between particulate air pollution and progression of atherosclerosis, …

Immediate effects of particulate air pollutants on heart rate and respiratory rate in hypertensive rats

C Nadziejko, K Fang, E Nadziejko, SP Narciso… - Cardiovascular …, 2002 - Springer
… Time-series studies have shown that the lag time between elevated particulate air pollution
(PM) … In this study, spontaneously hypertensive rats (SHRs) with surgically implanted blood …

Effects of concentrated ambient particles on heart rate, blood pressure, and cardiac contractility in spontaneously hypertensive rats

CC Chang, JS Hwang, CC Chan, PY Wang… - Inhalation …, 2004 - Taylor & Francis
… Epidemiological studies have shown that particulate matter (PM) air pollution is associated
with … Recent studies have revealed an association between PM pollution and autonomic …

Exposure to concentrated ambient particulate matter induces reversible increase of heart weight in spontaneously hypertensive rats

Z Ying, X Xie, Y Bai, M Chen, X Wang, X Zhang… - Particle and fibre …, 2015 - Springer
… [7], suggesting that air pollution may also be associated with … exposure to diesel exhaust
air pollution during in utero and … study, we exposed spontaneously hypertensive rats (SHR) to …