Blockade of the renin-angiotensin-aldosterone system: effects on hypertensive target organ damage

AM Grandi, AM Maresca - Cardiovascular & Hematological …, 2006 - ingentaconnect.com
… (ACE) inhibitors, the angiotensin II AT1 receptors blockers (ARBs) and the aldosterone …
drugs on hypertensive target organ damage. THE RENIN-ANGIOTENSIN-ALDOSTERONE …

Direct renin inhibition with aliskiren in hypertension and target organ damage

DN Mu, FC Luft - Clinical Journal of the American Society of …, 2006 - journals.lww.com
… highly successful pharmacologic target, as … hypertension-related target organ damage.
However, compensatory increases in plasma renin levels that lead to adjustments in angiotensin

Mechanisms of target organ damage caused by hypertension: therapeutic potential

G Cohuet, H Struijker-Boudier - Pharmacology & therapeutics, 2006 - Elsevier
damages related to hypertension in these target organs and the mechanisms involved in the
pathogenesis of hypertension-… main biological effector of the renin angiotensin system (RAS)…

Effects of inhibition of the renin-angiotensin system on hypertension-induced target organ damage: clinical and experimental evidence

MR De Luca, D Sorriento, D Massa… - … Archives for Chest …, 2021 - monaldi-archives.org
Angiotensin II plays a key role in the control of several pathogenic mechanisms that ulti…
of hypertension-induced target organ damage. ACE, angiotensin converting enzyme. …

[HTML][HTML] Inhibition of the reninangiotensin system and target organ protection

J Iwanami, M Mogi, M Iwai, M Horiuchi - Hypertension Research, 2009 - nature.com
target organ damage induced by RAS in each organ and the effect of blockade of RAS, such
as with angiotensin … blockers (ARBs), on target organ damage are discussed, together with …

[HTML][HTML] Role of the renin-angiotensin-aldosterone system beyond blood pressure regulation: molecular and cellular mechanisms involved in end-organ damage …

N Muñoz-Durango, CA Fuentes, AE Castillo… - International journal of …, 2016 - mdpi.com
… in hypertensive … a renin-angiotensin-aldosterone system (RAAS) imbalance has on health
considerations above and beyond high blood pressure, such as fibrotic end-organ damage. …

Review of aldosterone-and angiotensin II-induced target organ damage and prevention

AD Struthers, TM MacDonald - Cardiovascular research, 2004 - academic.oup.com
… the risk of progressive target organ damage in patients with hypertension and heart failure.
This may … While both agents have been demonstrated to be effective antihypertensive agents, …

[HTML][HTML] Molecular interactions of arterial hypertension in its target organs

J Kućmierz, W Frąk, E Młynarska, B Franczyk… - International Journal of …, 2021 - mdpi.com
… in pathogenesis of AH and hypertension-related target organ damage. In our paper, …
renin-angiotensin-aldosterone system and oxidative stress in hypertensive induced organ damage

[HTML][HTML] … of plasma renin, angiotensin, and aldosterone levels to blood pressure variability and target organ damage in children with essential hypertension

Y Liu, Y Lin, MM Zhang, XH Li, YY Liu, J Zhao… - BMC Cardiovascular …, 2020 - Springer
angiotensin II and aldosterone, are associated with BPV and involved in the progression of
hypertensive target organ damage … and target organ damage (TOD) in hypertensive children …

The renin-angiotensin-aldosterone system: a specific target for hypertension management

MR Weir, VJ Dzau - American journal of hypertension, 1999 - academic.oup.com
… with advanced target organ injury, such as those with systolic heart failure or diabetic …
changes in hypertensive disease. Early clinical trials demonstrate that angiotensin receptor …