Hypertonic saline infusion in traumatic brain injury increases the incidence of pulmonary infection

G Coritsidis, N Diamond, A Rahman, P Solodnik… - Journal of Clinical …, 2015 - Elsevier
… The Elmhurst Hospital trauma center in New York City admits a large volume of TBI patients
to the surgical/trauma intensive care unit (STICU). We retrospectively identified 225 charts of …

Timing of hypertonic saline and airway clearance techniques in adults with cystic fibrosis during pulmonary exacerbation: pilot data from a randomised crossover study

K O'Neill, F Moran, MM Tunney… - BMJ open …, 2017 - bmjopenrespres.bmj.com
… timing of treatment with hypertonic saline (… treatment, it is unclear how the timing of inhaled
therapies impact on the effectiveness of ACT. Mucoactive agents such as hypertonic saline (…

Hypertonic saline for the treatment of intracranial hypertension

T Kheirbek, JL Pascual - Current neurology and neuroscience reports, 2014 - Springer
… This is typically accomplished with osmolar therapy, most commonly mannitol and hypertonic
saline. Recent human trials suggest that hypertonic saline may have a more profound and …

Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13

M Wohlauer, EE Moore, CC Silliman… - Critical care …, 2012 - journals.lww.com
… To our knowledge, this study is the first to propose nebulized HTS as a therapy for ALI/ARDS…
markers, and that even large volume normal saline resuscitation has been shown to have …

Use of hypertonic saline injection in trauma

AE Patanwala, A Amini, BL Erstad - American Journal of Health …, 2010 - academic.oup.com
… for the treatment of severe TBI, hypertonic saline may be … However, the high osmolarity of
hypertonic saline relative to … With an intact blood-brain barrier, hypertonic saline should pull …

[HTML][HTML] Efficacy of hypertonic saline versus isotonic saline among children with cystic fibrosis: A systematic review and meta-analysis

SE Ullah, MM Zahoor, S Gupta, S Boparai… - … Respiratory Therapy …, 2023 - ncbi.nlm.nih.gov
… Inhaled hypertonic saline (HS) reduces pulmonary exacerbations in patients with cystic
fibrosis (CF) aged 6 or more years. However, the effectiveness of HS in improving clinical …

Efficacy and safety of hypertonic saline solutions in the treatment of severe head injury

SJ Huang, L Chang, YY Han, YC Lee, YK Tu - Surgical neurology, 2006 - Elsevier
hypertonic saline (HS) in the treatment of intracranial hypertension after severe head injury.
… effective intravascular volume and cardiac output. Hypertonic saline also increases the air …

Effect of hypertonic saline, amiloride, and cough on mucociliary clearance in patients with cystic fibrosis.

M Robinson, JA Regnis, DL Bailey, M King… - American journal of …, 1996 - atsjournals.org
… This nebulizer has a high volume output (1.5ml/min) and a small dead volume (0.5 ml).
The nebulizer was connected to a 30-cm piece of corrugated tubing which in turn was connected …

[PDF][PDF] Hypertonic Saline Lowers Raised Intracranial Pressure in

DT Brock Fisher, B Peterson - Journal of neurosurgical …, 1992 - ether.stanford.edu
… for hypertonic solutions to work. … of hypertonic saline on raised intracranial pressure in
adults or children. In this study we measured the acute effects of intravenous hypertonic saline

Hyperosmolar therapy in the treatment of severe head injury in children: mannitol and hypertonic saline

JM Knapp - AACN Advanced Critical Care, 2005 - AACN
… may occur with continuous infusion or large volume administration of HTS, possibly …
volume is replaced with HTS.Hypokalemia can be seen with administration of hypertonic saline