[HTML][HTML] Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance

S Kaushik, JA Rodriguez-Navarro, E Arias, R Kiffin… - Cell metabolism, 2011 - cell.com
… in hypothalamic agouti-related peptide (AgRP) neuronshypothalamic autophagy mobilizes
neuron-intrinsic lipids to generate endogenous free fatty acids, which in turn regulate AgRP

[HTML][HTML] Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding

MO Dietrich, MR Zimmer, J Bober, TL Horvath - Cell, 2015 - cell.com
… we show that these neurons also … Agrp neuron activation in promoting repetitive/stereotypic
behaviors in mice, unmasking a previously unsuspected role for these hypothalamic neurons

Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

Y Mandelblat-Cerf, RN Ramesh, CR Burgess, P Patella… - Elife, 2015 - elifesciences.org
… in the arcuate nucleus of the hypothalamus (ARC)—are both … of AgRP neurons, we performed
optetrode electrophysiological recordings from AgRP neurons in awake, behaving AgRP-…

[HTML][HTML] Network of hypothalamic neurons that control appetite

JW Sohn - BMB reports, 2015 - ncbi.nlm.nih.gov
… regulation of neuronal circuit involving these neurons is … Thus, adequate knowledge of the
POMC and NPY/AgRP neuron … on the POMC and NPY/AgRP neuronal circuits, as well as …

Hypothalamic AgRPneurons control peripheral substrate utilization and nutrient partitioning

A Joly‐Amado, RGP Denis, J Castel, A Lacombe… - The EMBO …, 2012 - embopress.org
… are indispensible for the hypothalamic integration of energy balance. Here, we … for
AgRPneurons in the control of nutrient partitioning. We report that ablation of AgRPneurons leads …

AgRP neurons: Regulators of feeding, energy expenditure, and behavior

JD Deem, CL Faber, GJ Morton - The FEBS journal, 2022 - Wiley Online Library
… are associated with inhibition of hypothalamic Agrp mRNA expression [[150, 151]].
Combined with evidence that CRISPR-mediated deletion of the leptin receptor (LepR) from …

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

H Makimura, TM Mizuno, JW Mastaitis, R Agami… - BMC neuroscience, 2002 - Springer
… of an endogenous neuronal gene. This study also directly indicates that hypothalamic
AGRP regulates metabolic rate. The observation that reduction of AGRP mRNA would produce …

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

TM Hahn, JF Breininger, DG Baskin… - Nature neuroscience, 1998 - nature.com
… Moreover, these NPY neurons coexpress mRNA encoding Agouti-related protein (Agrp), an
… Our findings suggest that hypothalamic NPY/Agrp neurons constitute a unique cell type that …

Functional ontogeny of hypothalamic Agrp neurons in neonatal mouse behaviors

MR Zimmer, AHO Fonseca, O Iyilikci, R Dai Pra… - Cell, 2019 - cell.com
… Chemogenetic overactivation of these neurons further increased emission of these ultrasonic
… of hypothalamic Agrp neurons during mouse development, suggesting these neurons

[HTML][HTML] Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism

G Marcelin, YH Jo, X Li, GJ Schwartz, Y Zhang… - Molecular …, 2014 - Elsevier
… findings support a mechanism by which FGF19 inhibits hypothalamic AGRP/NPY neurons. …
of hypothalamic Agrp and Npy mRNA, further implying that it prevented AGRP/NPY neuron