Endocrine and neuroanatomic features associated with weight gain and obesity in adult patients with hypothalamic damage

C Daousi, AJ Dunn, PM Foy, IA MacFarlane… - The American journal of …, 2005 - Elsevier
… can result from pituitary damage in the absence of hypothalamic involvement, and …
hypothalamic damage. However, growth hormone deficiency can also reflect hypothalamic damage, …

Weight gain in craniopharyngioma-a model for hypothalamic obesity

A Ahmet, S Blaser, D Stephens, S Guger… - Journal of Pediatric …, 2006 - degruyter.com
… Increased BMI SDS from 0-12 months was significantly associated with post-operative
MRI evidenced hypothalamic damage and higher BMI at presentation (p <0.05). …

Expanding the definition of hypothalamic obesity

I Hochberg, Z Hochberg - Obesity Reviews, 2010 - Wiley Online Library
… for excision of hypothalamic tumours. However, polyphagia and weight gain complicate other
disorders related to the hypothalamus, including those that cause structural damage to the …

Hypothalamic obesity in humans: what do we know and what can be done?

J Pinkney, J Wilding, G Williams… - Obesity …, 2002 - Wiley Online Library
… In conclusion, a variety of mechanisms probably contribute to weight gain, particularly in the
post-operative setting, in patients with hypothalamic damage. The contribution of individual …

Semiquantitative analysis of hypothalamic damage on MRI predicts risk for hypothalamic obesity

CL Roth, H Eslamy, D Werny, C Elfers, ML Shaffer… - …, 2015 - Wiley Online Library
weight gain and its resultant cardiometabolic abnormalities frequently occur in patients with
tumors in the hypothalamic region leading to hypothalamic … and hypothalamic structures and …

Obesity in childhood craniopharyngioma: relation to post-operative hypothalamic damage shown by magnetic resonance imaging

CJ De Vile, DB Grant, RD Hayward… - The Journal of …, 1996 - academic.oup.com
… Almost 30% of our patients had anorexia with poor weight gain or weight loss at presentation.
While this may have been secondary to associated symptoms of intracranial …

Postoperative hypothalamic damage predicts postoperative weight gain in patients with adult‐onset craniopharyngioma

J Wu, J Fu, ZJ Huang, SH Xie, B Tang, X Wu, ZG Tong… - …, 2022 - Wiley Online Library
… Additionally, we determined the role of hypothalamic damage evaluated by aforementioned
assessment systems in predicting postoperative HO and weight gain via multivariable …

Treatment of acquired hypothalamic obesity: now and the future

P Dimitri - Frontiers in Endocrinology, 2022 - frontiersin.org
… of sympathetic outflow from the hypothalamus secondary to hypothalamic damage will
result in … hormone from the hypothalamus (TRH), can compound excessive weight gain if left …

Lateral hypothalamic damage and body weight regulation: role of gender, diet, and lesion placement

AN Van den Pol - American Journal of Physiology …, 1982 - journals.physiology.org
… No supranormal weight gain (7) … of weight gain followed by maintenance of this supranormal
BW; the OVX and LH-OVX groups in this study went through a second dynamic weight gain

Weight regulation in normal and hypothalamic hyperphagic rats.

BG Hoebel, P Teitelbaum - Journal of Comparative and …, 1966 - psycnet.apa.org
… To induce overeating and weight gain in normal rats without brain damage, we used periodic
injections of long acting insulin (Mackay, Callaway, & Barnes, 1940). Protamine zinc insu…