… reactive oxygen species (ROS) generated by mitochondrial complex III are required for hypoxic
activation … about the role of mitochondrial ROS in HIF activation, as well as implications of …

… mitochondrial role in hypoxia, focusing mainly on their role in cellular energy and reactive
oxygen species … expression and that mitochondrial reactive oxygen species are not involved in …

… failure of ρ cells to activate HIF-1 during hypoxia relates to their failure to generate mitochondrial
ROS. However, mitochondria also generate ATP, and hypoxic activation of HIF-1 may …

… Here we show that hypoxia activates AMPK through LKB1 … Hypoxia increased reactive
oxygen species (ROS) levels and the antioxidant EUK-134 abolished the hypoxic activation of …

… Hypoxia-induced mitochondrial ROS are required for elevation of cytosolic … hypoxia,
mitochondrial production of ROS leads to activation of NADPH oxidases, further amplifying the ROS …

… roles of mitochondrial ROS and PKCɛ in the hypoxic activation of Nox … hypoxia activates
Nox in pulmonary, but not mesenteric, arteries. The activation of Nox is important for the hypoxia…

… Furthermore, p38α MAPK is activated by mitochondrial ROS during hypoxia (… mitochondrial
oxidant activation of the p38 MAPK signaling pathway is required for the hypoxic activation of …

… mitochondrial ROS in hypoxia is associated with hypoxia-inducible factor 1α (HIF-1α) stabilization
[30], [32], we reasoned that if RET was operating under hypoxia … or in hypoxia (Fig. 3de…

… We believe that mitochondrial ROS inhibit prolyl hydroxylase enzymatic activity in a similar
fashion to anoxia, H2O2, DFX, and cobalt chloride. Inhibition of hydroxylase activity leads to …

… Mitochondrial ROS production is modulated largely by the … that under hypoxic conditions,
the mitochondrial respiratory … The third major target of mitochondrial ROS is membrane lipids. …