The SDF-1/CXCR4 axis in stem cell preconditioning

C Cencioni, MC Capogrossi… - Cardiovascular …, 2012 - academic.oup.com
preconditioning (PC), which is a well-known protective phenomenon for tissue ischaemia. The
positive effect of both hypoxic … -single exposure to exogenous SDF-1, hypoxia, or acidosis. …

Hypoxic preconditioning enhances cellular viability and pro-angiogenic paracrine activity: the roles of VEGF-A and SDF-1a in rat adipose stem cells

Y Zhao, M Zhang, G Lu, B Huang, D Wang… - Frontiers in Cell and …, 2020 - frontiersin.org
… /VEGFR2 and SDF-1a/CXCR4 … and SDF-1a/CXCR4 axes may synergistically promote
angiogenesis by activating Akt. Collectively, our findings demonstrate that hypoxic preconditioning

Hypoxic Preconditioning Effects of Bone Marrow-derived Culture Mesenchymal Stem Cells on CD31+ Expression, Vascular Endothelial Growth Factors-a (VEGF-A) …

AF Muzakkir, IGR Suryawan… - IOP Conference Series …, 2020 - iopscience.iop.org
… in the preconditioning technique. In this case, hypoxic preconditioning can increase its
potential… This research is needed to find out the effect of hypoxia preconditioning (HPC) with 1% …

[HTML][HTML] Hypoxic preconditioning effect on stromal cells derived factor-1 and CXC chemokine receptor type 4 expression in Wistar rat's (Rattus norvegicus) bone …

SWM Mulyani, DS Ernawati, ER Astuti… - Veterinary …, 2018 - ncbi.nlm.nih.gov
… effect of hypoxic precondition in the cell culture using immunofluorescence and
immunocytochemical indicated strongly expressed of SDF-1 and CXCR4 after 48 h hypoxic

Hypoxic preconditioning combined with microbubble-mediated ultrasound effect on MSCs promote SDF-1/CXCR4 expression and its migration ability: an in vitro study

L Li, S Wu, P Li, L Zhuo, Y Gao, Y Xu - Cell biochemistry and biophysics, 2015 - Springer
… effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US)
on the SDF-1/… Using the optimum irradiation parameters, the concentration of SDF-1 in the …

The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury

H Liu, S Liu, Y Li, X Wang, W Xue, G Ge, X Luo - PloS one, 2012 - journals.plos.org
… that, at least in NP-MSCs, SDF-1α preconditioning has no effect on the expression of CXCR4
… , SDF-1α preconditioned HP-MSCs are markedly protected against H 2 O 2 , and this SDF-…

Hypoxic preconditioning enhances dental pulp stem cell therapy for infection-caused bone destruction

Y Wu, F Huang, X Zhou, S Yu, Q Tang, S Li… - … Engineering Part A, 2016 - liebertpub.com
SDF-1 and CXCR4 might participate in hypoxic … of hypoxic preconditioned hDPSCs can
result in nearly complete reversion of bone resorption in mice receiving hypoxic preconditioned

Hypoxic preconditioning improves survival of cardiac progenitor cells: role of stromal cell derived factor-1α–CXCR4 axis

F Yan, Y Yao, L Chen, Y Li, Z Sheng, G Ma - PloS one, 2012 - journals.plos.org
… To determine whether hypoxia preconditioning will influence CPC mobility toward SDF-1,
we performed an in vitro migration assay, and the c-kit+ CPCs were placed under either …

Stromal cell-derived factor 1 (SDF-1) signaling and tissue homeostasis

ZN Maan, MR Borrelli, KS Houschyar… - … medicine and plastic …, 2019 - Springer
… promoter region of the SDF-1 gene contains hypoxia inducible factor-1 (HIF-1) binding sites,
… that SDF-1 expression is upregulated in endothelial cells by HIF-1α [14, 15]. HIF-1 consists …

Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs

H Liu, W Xue, G Ge, X Luo, Y Li, H Xiang, X Ding… - Biochemical and …, 2010 - Elsevier
… indicated that sublethal hypoxic preconditioning (HP) of bone … stromal-derived factor-1 (SDF-1)
receptors, CXCR4 and … or sublethal hypoxia followed by 6 h of 1–100 ng/ml SDF-1α …