… synergistic role of hypoxic preconditioning and spheroid formation on MSCs and their ability
to repair a critical-sized bone defect. Hypoxic-preconditioned MSC spheroids were more …

… have assessed the therapeutic potential of hypoxia preconditioned stem cells in clinic. For
example, intracoronary administration of hypoxia preconditioned of hBM-MSCs after acute …

… 375, bone morphogenetic protein-2, and mutant hypoxia-inducible … bone defect [39]; one
study performed a segmental radius … bone formation was observed when the bone defects were …

… implanted in a CAM for 10 days showed similar results in defect area reduction for a 0.9
mm drilled defect [48]. A 2 mm segmental bone defect in ED18 chick femurs treated with bone …

… bone defects, and longer healing time. This review focuses on the impact of high-altitude
hypoxia on bone defect … mechanisms of abnormal bone defect repair in hypoxic environments, …

… R, Deng L, Qiu S (2012) New bone formation in a true bone ceramic scaffold loaded with
desferrioxamine in the treatment of segmental bone defect: a preliminary study. J Orthop Sci 17(…

… Hypoxic preconditioning of MSCs improved cell survival in a … ), and bone formation in
critical-sized femoral defects (6). The … preconditioned human BMA in an orthotopic bone defect. …

… Rats with critical-sized calvarial defects treated with hydrogels containing DMOG preconditioned
ASCs had more bone regeneration and new vessel formation than rats treated with a …

… The craniomaxillofacial bone regeneration is done under the hypoxia microenvironment, in
… activation under hypoxia conditions are unknown. In this study, the calvarial bone defect was …

… control or hypoxia condition into rat calvarial bone defects (… that the bone formation increased
over time in both defects … In contrast with our results, hypoxia-preconditioned human MSCs …