Hypoxic preconditioning of mesenchymal stem cells with subsequent spheroid formation accelerates repair of segmental bone defects
… formation. This study investigated the potentially synergistic role of hypoxic preconditioning
and spheroid formation on … Hypoxic-preconditioned MSC spheroids were more resistant to …
and spheroid formation on … Hypoxic-preconditioned MSC spheroids were more resistant to …
Formation of spheroids by dental pulp cells in the presence of hypoxia and hypoxia mimetic agents
… Thus, pre-conditioning cells during spheroid formation could … of spheroid formation and
the impact of HMA and hypoxia. … for pre-conditioning of DPC during spheroid formation might …
the impact of HMA and hypoxia. … for pre-conditioning of DPC during spheroid formation might …
Three-dimensional Spheroid Culture Combined with Hypoxic Preconditioning Can Promote the Proliferation and Osteogenic Differetiation of BMSCs in Low-oxygen …
X Qiu, Z Feng, G Liu, R Miao, X Tan, J Tao, B Yang… - 2022 - researchsquare.com
… Additionally, the formation of BMSC spheroids can effectively up-regulate growth factors, …
was explored using hypoxic preconditioning and the formation of BMSCs spheroids. This …
was explored using hypoxic preconditioning and the formation of BMSCs spheroids. This …
… , a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids
MHG Costa, J Serra, TC McDevitt… - Biotechnology …, 2021 - Wiley Online Library
… cell preconditioning strategies, namely through hypoxic stimuli and … of MSC spheroids to
hypoxic cues or hypoxic-mimicking … Phase images of 500 cells-containing spheroids formed …
hypoxic cues or hypoxic-mimicking … Phase images of 500 cells-containing spheroids formed …
Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells
… , spheroid cultures precondition hADSCs to a hypoxic environment, and grafting hADSCs
as spheroids to … The efficiency of hADSC spheroid formation was calculated using the initial …
as spheroids to … The efficiency of hADSC spheroid formation was calculated using the initial …
ASC spheroid geometry and culture oxygenation differentially impact induction of preangiogenic behaviors in endothelial cells
ML Skiles, B Hanna, L Rucker, A Tipton… - Cell …, 2015 - journals.sagepub.com
… ASC Spheroid Formation ASC spheroids were formed in a manner previously detailed (43).
Cells in … This supports the suggestion that hypoxic preconditioning can prime ASCs to more …
Cells in … This supports the suggestion that hypoxic preconditioning can prime ASCs to more …
Pre-conditioning mesenchymal stromal cell spheroids for immunomodulatory paracrine factor secretion
JA Zimmermann, TC Mcdevitt - Cytotherapy, 2014 - Elsevier
… spheroids with diameters >100 μm expressed more hypoxia-induced survival factors such as
hypoxia-… Taken together, although human MSC spheroid formation increased the secretion …
hypoxia-… Taken together, although human MSC spheroid formation increased the secretion …
Use of culture geometry to control hypoxia-induced vascular endothelial growth factor secretion from adipose-derived stem cells: optimizing a cell-based approach to …
ML Skiles, S Sahai, L Rucker… - Tissue Engineering Part …, 2013 - liebertpub.com
… of spheroid size on hypoxia-inducible transcription factor (HIF)-1 activity in spheroid cultures
… (B) Diameter of spheroids formed by centrifugally pelleting different numbers of ADSCs. …
… (B) Diameter of spheroids formed by centrifugally pelleting different numbers of ADSCs. …
Hypoxic preconditioning enhances survival of human adipose-derived stem cells and conditions endothelial cells in vitro
SL Stubbs, STF Hsiao, HM Peshavariya… - Stem cells and …, 2012 - liebertpub.com
… Akt in hypoxia-induced ASC survival. Importantly, we showed that media derived from
hypoxic preconditioned ASC support endothelial cell survival and endothelial tube formation in …
hypoxic preconditioned ASC support endothelial cell survival and endothelial tube formation in …
[HTML][HTML] Pre-conditioning with IFN-γ and hypoxia enhances the angiogenic potential of iPSC-derived MSC secretome
S Wang, F Umrath, W Cen, AJ Salgado, S Reinert… - Cells, 2022 - mdpi.com
… under IFN-γ and hypoxic stimulation (IFN-H). Tube formation and wound healing assays …
Sprouting assays demonstrated that within Coll/HA scaffolds, HUVECs spheroids formed …
Sprouting assays demonstrated that within Coll/HA scaffolds, HUVECs spheroids formed …
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