Effects of hypoxia on stress proteins in the piglet brain at birth

M Chiral, JF Grongnet, JC Plumier, JC David - Pediatric research, 2004 - nature.com
piglet model can be used to evaluate the impact of hypoxia at the molecular level as
demonstrated by other groups. The present piglet … associated with hypoxia and correlating the …

Early regional response of apoptotic activity in newborn piglet brain following hypoxia and ischemia

A Pirzadeh, A Mammen, J Kubin, E Reade, H Liu… - Neurochemical …, 2011 - Springer
… the brain of piglets subjected to precisely controlled hypoxic and ischemic insults: 1 h hypoxia
(… Caspase-3 between sham operated, hypoxic and ischemic groups. There were significant …

N-acetylcysteine improves hemodynamics and reduces oxidative stress in the brains of newborn piglets with hypoxia-reoxygenation injury

JQ Liu, TF Lee, C Chen, DL Bagim… - Journal of …, 2010 - liebertpub.com
… NAC on HR-induced brain injury. We hypothesized that the administration of NAC after the
reoxygenation of hypoxic newborn piglets would alleviate HR-induced brain injury 48 h after …

Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain

R Dégı̀, F Bari, N Thrikawala, TC Beasley… - Developmental brain …, 1998 - Elsevier
… to reduce brain damage in neonatal pups following hypoxia–ischemia. In … Since PGHS-2
induction in response to hypoxia in … in protecting the brain following ischemic stress and thereby …

Non-invasive and quantitative near-infrared haemoglobin spectrometry in the piglet brain during hypoxic stress, using a frequency-domain multidistance instrument

DM Hueber, MA Franceschini, HY Ma… - Physics in medicine …, 2001 - iopscience.iop.org
… We have performed a number of hypoxic stress tests in newborn piglets while monitoring
brain … haemoglobin concentration and saturation in five piglets while inspired oxygen per cent (…

Apoptosis and necrosis in the newborn piglet brain following transient cerebral hypoxia–ischaemia

X Yue, H Mehmet, J Penrice, C Cooper… - Neuropathology and …, 1997 - Wiley Online Library
… The piglets were then resuscitated by releasing the carotid occluders and returning arterial
piglets. Six sham-operated control piglets that were not subjected to acute cerebral hypoxia–…

Sulforaphane protects piglet brains from neonatal hypoxic-ischemic injury

B Wang, E Kulikowicz, JK Lee, RC Koehler… - Developmental …, 2021 - karger.com
… The larger gyrencephalic piglet brain permits the study of selective cortical areas and …
hypoxia, followed by asphyxia in newborn piglets, to study the effects of sulforaphane in HI brains

DHA reduces oxidative stress after perinatal asphyxia: a study in newborn piglets

R Solberg, M Longini, F Proietti, S Perrone, C Felici… - Neonatology, 2017 - karger.com
… Conclusions: The present study demonstrates that DHA administration after severe hypoxia
in newborn piglets has an antioxidative effect in the brain, suggesting a protective potential …

Effect of hypoxia on DNA fragmentation in different brain regions of the newborn piglet

JC David, JF Grongnet - Molecular Reproduction and …, 2000 - Wiley Online Library
piglet brain following different times of normobaric hypoxia (5% O2, 95% N2). After 1 hr of
hypoxia… in these areas of the brain when the animals were kept under hypoxia for times up to 8 …

Influence of hypoxia and hypoxia/hypercapnia upon brain and blood peroxidative and glutathione status in normal weight and growth-restricted newborn piglets

A Barth, R Bauer, T Gedrange, B Walter… - Experimental And …, 1998 - Elsevier
… the brain support the hypothesis that oxidative stress plays a role in neuronal damage after
hypoxic stress, but the brain of IUGR did not reveal a special response to moderate hypoxia. …