[HTML][HTML] iRNA-PseKNC (2methyl): Identify RNA 2'-O-methylation sites by convolution neural network and Chou's pseudo components
Abstract The 2'-O-methylation transferase is involved in the process of 2'-O-methylation. In
catalytic processes, the 2-hydroxy group of the ribose moiety of a nucleotide accept a methyl
group. This methylation process is a post-transcriptional modification, which occurs in
various cellular RNAs and plays a vital role in regulation of gene expressions at the post-
transcriptional level. Through biochemical experiments 2'-O-methylation sites produce good
results but these biochemical process and exploratory techniques are very expensive. Thus …
catalytic processes, the 2-hydroxy group of the ribose moiety of a nucleotide accept a methyl
group. This methylation process is a post-transcriptional modification, which occurs in
various cellular RNAs and plays a vital role in regulation of gene expressions at the post-
transcriptional level. Through biochemical experiments 2'-O-methylation sites produce good
results but these biochemical process and exploratory techniques are very expensive. Thus …
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