Genomic analysis of the carboxylesterases: identification and classification of novel forms

ET Williams, H Wang, SA Wrighton, YW Qian… - Molecular Phylogenetics …, 2010 - Elsevier
… List of carboxylesterase genes used in this study from non-mammals. These genes are first
being reported in this study and were identified through genomic searches using Ensembl. …

The mammalian carboxylesterases: from molecules to functions

T Satoh, M Hosokawa - Annual review of pharmacology and …, 1998 - annualreviews.org
… similarity of the characteristics, we propose to classify carboxylesterase isozymes into four
… forms of carboxylesterase isozymes (more than 60% homology of human carboxylesterase). …

[PDF][PDF] Carboxylesterases: sources, characterization and broader applications

S Sood, A Sharma, N Sharma, SS Kanwar - Insight Enzym Res, 2016 - researchgate.net
… Human genome organization database listed five types of carboxylesterase genes family
CES1… also includes structures of many mammalian carboxylesterase [19]. In mammals, the first …

Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans

M Hosokawa, T Maki, T Satoh - Archives of biochemistry and biophysics, 1990 - Elsevier
… of carboxylesterase, designated as RLl, RL2, and RHl (10). These three carboxylesterase
… The present study was undertaken to investigate the characteristics of carboxylesterase

Systematic identification and characterization of carboxylesterases in cynomolgus macaques

Y Uno, S Uehara, M Hosokawa, T Imai - Drug Metabolism and Disposition, 2014 - ASPET
Carboxylesterase (CES) is important for detoxification of … characterized cDNAs for CES
homologous to human CES1, CES2, and CES5A in cynomolgus macaques. By genome analysis, …

Identification and characterization of novel benzil (diphenylethane-1, 2-dione) analogues as inhibitors of mammalian carboxylesterases

RM Wadkins, JL Hyatt, X Wei, KJP Yoon… - Journal of medicinal …, 2005 - ACS Publications
… To identify such inhibitors, we applied Telik's lead technology TRAP (target-related affinity …
identified an analogue of benzil that selectively inhibited a variety of CEs. Following analysis

Identification and characterization of hepatic carboxylesterases hydrolyzing hydrocortisone esters

B Ali, S Kaur, EC James, SS Parmar - Biochemical pharmacology, 1985 - Elsevier
… the existence of three distinct carboxylesterases involved in the … of nonspecific microsomal
carboxylesterase acting on p-… also differed from nonspecific carboxylesterases. The activity of …

Carboxylesterases: structure, function and polymorphism in mammals

T Satoh, M Hosokawa - Journal of Pesticide Science, 2010 - jstage.jst.go.jp
… of carboxylesterase isozymes, we propose a novel nomenclature and classification of mammalian
carboxylesterases on the … of carboxylesterases by xenobiotics, and the involvement of …

[HTML][HTML] Identification, Expression, and Purification of a Pyrethroidhydrolyzing Carboxylesterase from Mouse Liver Microsomes*[boxs]

JE Stok, H Huang, PD Jones, CE Wheelock… - Journal of Biological …, 2004 - ASBMB
… 315, 208-222) and subsequently identified as a carboxylesterase (NCBI accession number
BAC36707)… By isolating specific carboxylesterases we may begin to understand their relative …

Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases

MK Ross, A Borazjani, CC Edwards… - Biochemical pharmacology, 2006 - Elsevier
… Two major carboxylesterases have been identified in human liver and are termed hCE-1 …
The primary aim of this study was to examine whether the human carboxylesterases hCE-1 and …