[HTML][HTML] Identification of polymorphisms in 12q24. 1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association …
Y Yamada, J Sakuma, I Takeuchi, Y Yasukochi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… the SNPs identified in the present study are in linkage disequilibrium with other polymorphisms
in … (5) Four SNPs identified as susceptibility loci for hypertension were not associated with …
in … (5) Four SNPs identified as susceptibility loci for hypertension were not associated with …
P1337 Identification of 12q24. 1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese individuals by exome-wide association studies
H Horibe, K Kato, M Oguri, T Fujimaki… - European Heart …, 2017 - academic.oup.com
P1337Identification of 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood
pressure in Japanese individuals by exome-wide association studies | European Heart …
pressure in Japanese individuals by exome-wide association studies | European Heart …
120 Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in Japanese
H Horibe, K Kato, M Oguri, T Fujimaki… - European Heart …, 2018 - academic.oup.com
… identified definitively. Although recent genome-wide association studies have identified various
single nucleotide polymorphisms … hypertension, it may identify novel genetic variants that …
single nucleotide polymorphisms … hypertension, it may identify novel genetic variants that …
Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians
L Bian, RL Hanson, YL Muller, L Ma… - Diabetologia, 2010 - Springer
… in Pima Indians identified a variant within the ACAD10 gene … four tag single nucleotide
polymorphisms (SNPs) in a … the entire ACAD10 locus and the 5′ region of the BRAP gene. These …
polymorphisms (SNPs) in a … the entire ACAD10 locus and the 5′ region of the BRAP gene. These …
Evaluation of pleiotropic effects among common genetic loci identified for cardio-metabolic traits in a Korean population
YK Kim, MY Hwang, YJ Kim, S Moon, S Han… - Cardiovascular …, 2016 - Springer
… There were numerous direct protein–protein interactions for the three genes: 12 interactions
for ALDH2, one interaction for ACAD10 and 15 interactions for BRAP. According to this …
for ALDH2, one interaction for ACAD10 and 15 interactions for BRAP. According to this …
Potential mechanisms underlying the association between single nucleotide polymorphism (BRAP and ALDH2) and hypertension among elderly Japanese population
Y Shimizu, K Arima, Y Noguchi, SY Kawashiri… - Scientific Reports, 2020 - nature.com
… polymorphism (SNP) (rs3782886) in breast cancer suppressor BRCA1-related associated
protein (BRAP… Another study reported that BRAP activates inflammatory cascades, increasing …
protein (BRAP… Another study reported that BRAP activates inflammatory cascades, increasing …
Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension
A Chida-Nagai, M Shintani, H Sato, T Nakayama, M Nii… - Plos one, 2019 - journals.plos.org
… Arg554Leu-BRAP induced decreased apoptosis of hPASMCs compared with wild-type
BRAP. In conclusion, we have identified a novel variant of BRAP in a Japanese family with PAH …
BRAP. In conclusion, we have identified a novel variant of BRAP in a Japanese family with PAH …
Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach
L Wang, F Xu, A Brickell, N Sun, X Mao… - Molecular Genetics and …, 2020 - Springer
… Totally, we identified 24 significant SNPs associated with stroke conditioned on BMI, which
were annotated to 35 genes and located on nine different chromosomes (Table S2 and Fig. …
were annotated to 35 genes and located on nine different chromosomes (Table S2 and Fig. …
A genome-wide association study of a coronary artery disease risk variant
JY Lee, BS Lee, DJ Shin, K Woo Park, YA Shin… - Journal of human …, 2013 - nature.com
… SNP (rs3782886) in BRAP identified in the Japanese GWA study is polymorphic in … is
polymorphic only in Europeans. In our study, the strong evidence of CAD association was identified …
polymorphic only in Europeans. In our study, the strong evidence of CAD association was identified …
P1338 Mutations in RBM20 and titin cause left ventricular non-compaction cardiomyopathy
F Sedaghat-Hamedani, J Haas, F Zhu… - European Heart …, 2017 - academic.oup.com
… Background: Although several polymorphisms have been … 12q24.1 or in ACAD10 or
BRAP being novel determinants of … Purpose: We aimed to identify novel and population-specific …
BRAP being novel determinants of … Purpose: We aimed to identify novel and population-specific …