Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat

TM Maher, ME Strek - Respiratory research, 2019 - Springer
… Two antifibrotic therapies have been approved for the treatment of IPF: nintedanib and …
IPF and the utility of antifibrotic therapies, with a focus on the importance of early treatment. …

Antifibrotic therapy for fibrotic lung disease beyond idiopathic pulmonary fibrosis

BF Collins, G Raghu - European Respiratory Review, 2019 - Eur Respiratory Soc
… Two antifibrotic medications (nintedanib and pirfenidone) were recommended (conditionally)
for the treatment of patients with idiopathic pulmonary fibrosis (IPF) in the 2015 IPF …

Clinical effectiveness of antifibrotic medications for idiopathic pulmonary fibrosis

TM Dempsey, LR Sangaralingham, X Yao… - American journal of …, 2019 - atsjournals.org
… that differences in the dose, duration, or mode of steroid therapy between the untreated
and antifibrotic therapy groups could explain some of the observed differences in survival. …

Antifibrotic therapy for idiopathic pulmonary fibrosis

PS Acharya, DA Zisman - Clinical Pulmonary Medicine, 2001 - journals.lww.com
therapy, alternative approaches to the treatment of IPF are being pursued. The following
is a brief discussion of antifibrotic therapy and other promising agents in the treatment of IPF. …

Idiopathic pulmonary fibrosis: recent advances on pharmacological therapy

P Spagnolo, TM Maher, L Richeldi - Pharmacology & therapeutics, 2015 - Elsevier
… The assumption behind such restricted criteria, which are adopted for most IPF clinical
trials, is mainly that advanced disease is less likely to be amenable to any anti-fibrotic therapy, …

Current and future therapeutic approaches in idiopathic pulmonary fibrosis

D Bouros, KM Antoniou - European Respiratory Journal, 2005 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a lethal form of idiopathic diffuse lung disorders for which
no current treatment is effective. The aim of the present study was to systematically review …

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

PM George, AU Wells, RG Jenkins - The Lancet Respiratory …, 2020 - thelancet.com
idiopathic pulmonary fibrosis (IPF), namely increasing age, male sex, and comorbidities such
as hypertension and diabetes. However, the role of antifibrotic therapy … potential antifibrotic

Prognosis of idiopathic pulmonary fibrosis without anti-fibrotic therapy: a systematic review

YH Khor, Y Ng, H Barnes, NSL Goh… - European …, 2020 - Eur Respiratory Soc
… is essential for treatment decisions in patients with idiopathic pulmonary fibrosis (IPF). This
review aimed to evaluate the prognosis of patients with IPF without anti-fibrotic therapy. We …

Antifibrotic therapy for the treatment of pulmonary fibrosis

JA Lasky, LA Ortiz - The American journal of the medical sciences, 2001 - Elsevier
… initial treatment of idiopathic pulmonary fibrosis, yet a retrospective study of 127 patients
with cryptogenic fibrosing alveolitis published in 1980 showed that only 17% had an objective …

Impact of antifibrotic therapy on mortality and acute exacerbation in idiopathic pulmonary fibrosis: a systematic review and meta-analysis

T Petnak, P Lertjitbanjong, C Thongprayoon, T Moua - Chest, 2021 - Elsevier
… Studies were included if they were original articles comparing mortality or AE events in
IPF patients with and without antifibrotic treatment. Relative risk (RR) with 95%CI was pooled …