Disease stratification in idiopathic pulmonary fibrosis: the dawn of a new era?

TM Maher - European Respiratory Journal, 2014 - Eur Respiratory Soc
Research into idiopathic pulmonary fibrosis (IPF) has been rapidly gathering pace over the
past few years. This has been driven by a number of important factors, including the …

[HTML][HTML] Validation of the risk stratification score in idiopathic pulmonary fibrosis: study protocol of a prospective, multi-centre, observational, 3-year clinical trial

GM Manzetti, K Hosein, MJ Cecchini, K Kwan… - BMC Pulmonary …, 2021 - Springer
… NCT02632123 “Validation of the risk stratification score in idiopathic pulmonary fibrosis”. …
(% predicted) to stratify patients in 3 different stages of the disease. This model was validated …

Acute exacerbations of idiopathic pulmonary fibrosis: Does clinical stratification or steroid treatment matter?

S Cuerpo, J Moises… - … Disease, 2019 - journals.sagepub.com
idiopathic pulmonary fibrosis (IPF) is defined as a sudden acceleration of the disease with the
appearance of pulmonary … differences according to clinical stratification (AE, suspected AE, …

Risk factors for disease progression in idiopathic pulmonary fibrosis

G Raghu, B Ley, KK Brown, V Cottin, KF Gibson… - Thorax, 2020 - thorax.bmj.com
… enrich or stratify a study population with patients at increased risk of events indicative of
disease … over 14 weeks is not apparently useful for stratification or enrichment. Here, more rapid …

[HTML][HTML] Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification

ALA Katzenstein, JL Myers - … journal of respiratory and critical care …, 1998 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF), also referred to as cryptogenic fibrosing alveolitis, is a
progressive interstitial lung disease … Our classification scheme for IPF is easily and consistently …

Pulmonary fibrosis in the era of stratified medicine

SK Mathai, CA Newton, DA Schwartz, CK Garcia - Thorax, 2016 - thorax.bmj.com
… The most widely replicated variant (rs35705950) is located in the promoter region of the
MUC5B gene and has been strongly associated with idiopathic pulmonary fibrosis (IPF) and …

Idiopathic pulmonary fibrosis: diagnosis, epidemiology and natural history

G Sgalla, A Biffi, L Richeldi - Respirology, 2016 - Wiley Online Library
… course of the disease and the identification of biomarkers of progression would lead to a
better stratification of the disease, essential for delivering individualized therapeutic strategies. …

Stratification of long-term outcome in stable idiopathic pulmonary fibrosis by combining longitudinal computed tomography and forced vital capacity

N Sverzellati, M Silva, V Seletti, C Galeone… - European …, 2020 - Springer
… In fact, major collinearity of VRS with the CALIPER-total volume of lung fibrosis was … for
stratification of outcome: we found that the relative change of total volume of lung fibrosis best fits …

Idiopathic pulmonary fibrosis: molecular endotypes of fibrosis stratifying existing and emerging therapies

D Magnini, G Montemurro, B Iovene, L Tagliaboschi… - Respiration, 2017 - karger.com
Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing
interstitial pneumonia of unknown causes. Current diagnostic criteria are based on radiological, …

[HTML][HTML] Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF)

T Win, NJ Screaton, JC Porter, B Ganeshan… - European journal of …, 2018 - Springer
… There is a lack of prognostic biomarkers in idiopathic pulmonary fibrosis (IPF) patients. The
objective of this study is to investigate the potential of 18 F-FDG-PET/ CT to predict mortality …