Integrative analyses of genes associated with idiopathic pulmonary fibrosis

H Wang, Q Xie, W Ou‐Yang… - Journal of Cellular …, 2019 - Wiley Online Library
… datasets of IPF were analyzed for a comprehensive analysis of potential genes associated
… with a single microarray analysis. Although a recent microarray analysis of IPF strongly …

[HTML][HTML] Identification of transcriptomic markers for developing idiopathic pulmonary fibrosis: an integrative analysis of gene expression profiles

D Li, Y Liu, B Wang - International Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) remains a lethal disease with unknown etiology and
unmet medical need. The aim of this study was to perform an integrative analysis of multiple …

Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis

SK Kim, SM Jung, KS Park, KJ Kim - BMC Pulmonary Medicine, 2021 - Springer
Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical burden. The
molecular signatures of IPF were analyzed to distinguish molecular subgroups and identify …

Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosis

P Zheng, S Sun, J Wang, ZJ Cheng, KC Lei… - Cellular and Molecular …, 2022 - Springer
… (IPF) is an interstitial lung disease characterized by chronic progressive pulmonary fibrosis
and a … Herein we provided a novel strategy to identify biomarkers by integrative analysis of …

Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression

P Ruan, JL Todd, H Zhao, Y Liu, R Vinisko… - Respiratory …, 2023 - Springer
… patients with non-idiopathic pulmonary fibrosis who were at high … Integrative multi-omics
analyses have identified molecular … using an unsupervised integrative clustering method would …

Integrated genomics reveals convergent transcriptomic networks underlying chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

RL Kusko, JF Brothers, J Tedrow, K Pandit… - American journal of …, 2016 - atsjournals.org
… IPF and emphysema involved an integrative analysis of the mRNA-seq and microRNA
array data generated on the same lung tissue samples. This analysis also revealed evidence …

Integrative analysis reveals the recurrent genetic etiologies in idiopathic pulmonary fibrosis

S Guo, Y Dong, C Wang, Y Jiang… - … Journal of Medicine, 2023 - academic.oup.com
lung disease with an unknown etiology. Current studies focus on revealing the genetic factors
in the risk of IPF, making the integrative analysis … through an integrative analysis of whole-…

Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis

I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing IIP that has no effective therapy with
a mortality rate higher than many cancers; median survival from the time of diagnosis being …

Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases

M Chen, Y Zhang, T Adams, D Ji, W Jiang, LV Wain… - Thorax, 2023 - thorax.bmj.com
… regions associated with idiopathic pulmonary fibrosis (IPF), … Methods We conducted integrative
analyses to improve the … performed transcriptome-wide association analysis (TWAS) of …

Integrative analysis of transcriptome-wide association study and mRNA expression profiles identifies candidate genes associated with idiopathic pulmonary fibrosis

W Gong, P Guo, L Liu, Q Guan, Z Yuan - Frontiers in Genetics, 2020 - frontiersin.org
… 38 common GO terms and 8 KEGG pathways shared by enrichment analysis of TWAS … by
hub gene and module analysis. In conclusion, through integrative analysis of TWAS and mRNA …