Idiopathic pulmonary fibrosis: molecular endotypes of fibrosis stratifying existing and emerging therapies
D Magnini, G Montemurro, B Iovene, L Tagliaboschi… - Respiration, 2017 - karger.com
… but cannot distinguish subtypes, and this is a major limit for their use in IPF diagnosis; however,
… In animal models of lung fibrosis, treatment with nintedanib is preventive and therapeutic …
… In animal models of lung fibrosis, treatment with nintedanib is preventive and therapeutic …
Identification of the molecular subgroups in idiopathic pulmonary fibrosis by gene expression profiles
N Zhang, Y Guo, C Wu, B Jiang… - … methods in medicine, 2021 - Wiley Online Library
… , the subtypes of IPF … subtypes of IPF obtained in the preliminary screening of this study
have certain guiding significance for development of new drugs, clinical treatment, and prognosis …
have certain guiding significance for development of new drugs, clinical treatment, and prognosis …
Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?
… causes implied for the specific subtypes. The causes of some subtypes are now known: giant-…
, IPF included several histopathological subtypes of interstitial lung disease, such as usual …
, IPF included several histopathological subtypes of interstitial lung disease, such as usual …
Idiopathic pulmonary fibrosis
L Richeldi, HR Collard, MG Jones - The Lancet, 2017 - thelancet.com
… , and treatment options available for patients with idiopathic … has improved understanding
of the mechanisms of lung fibrosis, … of patients with other progressive fibrotic lung diseases. …
of the mechanisms of lung fibrosis, … of patients with other progressive fibrotic lung diseases. …
Existing and emerging treatments for idiopathic pulmonary fibrosis
L Kolilekas, S Papiris, D Bouros - Expert Review of Respiratory …, 2019 - Taylor & Francis
… Introduction: Idiopathic pulmonary fibrosis (IPF) is a progressive and invariable fatal interstitial
lung disease. Current antifibrotic treatment halts disease progression but does not cure …
lung disease. Current antifibrotic treatment halts disease progression but does not cure …
Progress in understanding and treating idiopathic pulmonary fibrosis
JA Kropski, TS Blackwell - Annual review of medicine, 2019 - annualreviews.org
… in the evaluation and care of patients with idiopathic pulmonary fibrosis (IPF). In addition to
… underlie susceptibility to IPF and affect prognosis have raised the possibility of personalized …
… underlie susceptibility to IPF and affect prognosis have raised the possibility of personalized …
Molecular mechanisms of and possible treatment strategies for idiopathic pulmonary fibrosis
M Gharaee-Kermani, SH Phan - Current pharmaceutical design, 2005 - ingentaconnect.com
… pulmonary fibrosis, and includes a more detailed discussion of the potential points of therapeutic
attack in pulmonary fibrosis… Fibroblasts in a subtype fibrotic process include; a migratory …
attack in pulmonary fibrosis… Fibroblasts in a subtype fibrotic process include; a migratory …
Pharmacological treatment of idiopathic pulmonary fibrosis: an update
P Spagnolo, AU Wells, HR Collard - Drug Discovery Today, 2015 - Elsevier
… Idiopathic pulmonary fibrosis (IPF) is a progressive and almost invariably lethal disease that
… slowing disease progression with medication is possible. An improved understanding of …
… slowing disease progression with medication is possible. An improved understanding of …
Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis
GY Liu, GRS Budinger, JE Dematte - Bmj, 2022 - bmj.com
… treatment of idiopathic pulmonary fibrosis, as well as all active and completed phase 2 and
3 clinical trials of nintedanib and pirfenidone for the treatment … The subtypes most commonly …
3 clinical trials of nintedanib and pirfenidone for the treatment … The subtypes most commonly …
Prognosis of fibrotic interstitial pneumonia: idiopathic versus collagen vascular disease–related subtypes
JH Park, DS Kim, IN Park, SJ Jang… - American journal of …, 2007 - atsjournals.org
… The prognosis of patients with the usual interstitial … with idiopathic pulmonary fibrosis,
despite the same pathologic pattern. In contrast, in those with an NSIP pattern, the prognosis is …
despite the same pathologic pattern. In contrast, in those with an NSIP pattern, the prognosis is …