… on the potentially crucial role of IFN-γ in inhibiting HBV infection. IFNs are a family of … infection.
They include several members: type I IFN (α, β, ε, and ω), type II IFN (γ) and type III IFN (λ). …

… IFN-γ/TNF-α functional profile of HBV-specific CD4 T cells in 68 patients with chronic HBV
infection … Then, the IFN-γ/TNF-α functional profile of HBV-specific CD4 T cells was analyzed in …

… In summary, IFN-γ has significant beneficial effects on liver fibrosis in patients with chronic
HBV infection. Moreover, our data indicate that IFN-γ antagonizes the TGF-β/Smad pathway, …

… 50 years of age with HBeAg positive chronic hepatitis B infection were recruited for this study.
… -specific T cells was quantified by intra-cellular cytokine staining for IFN-γ. In brief, PBMCs …

… , thus non-cytopathic effector functions of CD4 + and CD8 + T cells, like the production of
antiviral cytokines (IFN-γ, TNFα), are indispensable to control HBV infection 2, 3 . During acute …

… +874AA genotype of the IFN-γ was greater in the intrauterine HBV infection group than in …
) + of IFN-γ CA microsatellite polymorphism was 11.90% in the intrauterine HBV infection group …

… Thirty-nine patients with chronic HBV infection were enrolled in this study (Table 1). All
patients were seropositive for hepatitis B surface Ag (HBs) and hepatitis B e Ag (HBs) for at least …

… of HBV infection by T cells via T-cell–derived antiviral cytokines using in vitro models of
HBV infection that establish a nuclear HBV cccDNA pool and set up co-culture models with …

… We showed that patients with chronic HBV infection had elevated IFN-γ levels. It has also
been shown that IFN-γ has both cytotoxic effect on hepatocytes (Toyonaga et al., 1994, Mancini …

… , and sustained suppression of HBV-DNA accompanied by biochemical … in the fight against
chronic HBV infection. Such drugs or … a cure for chronic HBV infection, as in the case of HCV. …