Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer

A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
… -1, TGF-β1, PI3K, ERK, Akt, and mTOR). This review describes the role of IGF-1 in glucose
metabolism in physiology and colorectal carcinogenesis, including the role of the insulin/IGF

Nutrition, insulin, IGF1 metabolism and cancer risk: a summary of epidemiological evidence

R Kaaks - Biology of IGF1: Its Interaction with Insulin in Health …, 2004 - Wiley Online Library
… and blood glucose profiles and serum insulin-like growth factorI concentrations in women
with polycystic ovaries. Horm Res 37:125^131 Probst-Hensch N, Yuan J, Stanczyk F et al 2001 …

Differential role of insulin/IGF-1 receptor signaling in muscle growth and glucose homeostasis

BT O'Neill, HPMM Lauritzen, MF Hirshman, G Smyth… - Cell reports, 2015 - cell.com
… To investigate to what extent insulin and/or IGF-1 signaling pathways control glucose
metabolism and protein homeostasis, we have deleted IRs, IGF1Rs, or both in skeletal muscle …

Insulin-like growth factor-1 deficiency and metabolic syndrome

GA Aguirre, JR De Ita, RG De La Garza… - Journal of translational …, 2016 - Springer
IGF-1 deficiency and metabolic syndrome. In this review, we will focus on the metabolic effects
of IGF-1, the concept of metabolic … , insulin resistance, increased glucose levels, obesity, …

Insulin-like growth factor 1 regulates developing brain glucose metabolism

CM Cheng, RR Reinhardt, WH Lee… - Proceedings of the …, 2000 - National Acad Sciences
… brain insulin-like growth factor 1 (Igf1) serves an essential, insulin-like role in promoting
neuronal glucose utilization and growth during this period. Brain 2-deoxy-d- [1- 14 C]glucose

Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226.

GG Freund, DT Kulas, RA Mooney - Journal of immunology …, 1993 - journals.aai.org
… (mouse), insulin and IGF-1 increased … and IGF-1 receptors are present in myeloma cell
lines. Through these receptors, insulin and IGF-1 regulate mitogenesis and glucose metabolism, …

Impact of glucose metabolism disorders on IGF-1 levels in patients with acromegaly

SC Dogansen, GY Yalin, S Tanrikulu… - … and Metabolic …, 2018 - thieme-connect.com
glucose metabolism abnormalities and their impact on IGF-1 … into three groups such as;
normal glucose tolerance (n=23, 25%… may be associated with glucose metabolism abnormalities. …

The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations

DE Berryman, CAM Glad, EO List… - Nature Reviews …, 2013 - nature.com
insulin-like growth factor 1 in most tissues, and together GH and insulin-like growth factor
1 exert powerful collective actions on fat, protein and glucose metabolism. Clinical trials …

A comparison of the effects of IGF‐I and insulin on glucose metabolism, fat metabolism and the cardiovascular system in normal human volunteers

DL Russell‐Jones, AT Bates… - European journal of …, 1995 - Wiley Online Library
glucose concentration was 4-98 i0-ll and 5-12:|:0-l8mmol 1'1 … Ra in addition to the stimulatory
effect on glucose Rd [8]. This … of the IGF-I infusion on glucose metabolism were slower in …

Altered liver expression of genes involved in lipid and glucose metabolism in mice with partial IGF-1 deficiency: an experimental approach to metabolic syndrome

JR De Ita, I Castilla-Cortázar, GA Aguirre… - Journal of translational …, 2015 - Springer
IGF-1 deficiency is able to alter the expression of genes involved in glucose and lipid metabolic
… -qPCR confirmation; serum levels of IGF-1, glucose, cholesterol and triglycerides were …