[HTML][HTML] EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO …

S Boeck, A Jung, RP Laubender, J Neumann… - British journal of …, 2013 - nature.com
… agents such as erlotinib or cetuximab. In contrast to the biomarker results of the PA.3 study,
we found a higher rate of KRAS wild-type patients within our translational study population (…

[HTML][HTML] Comparison of clinical outcomes following gefitinib and erlotinib treatment in non–small-cell lung cancer patients harboring an epidermal growth factor …

SH Lim, JY Lee, JM Sun, JS Ahn, K Park… - Journal of Thoracic …, 2014 - Elsevier
… versus chemotherapy as first-line treatment for patients with … III study), 9 a study conducted
in China comparing erlotinib and … patients, demonstrated significantly longer PFS with erlotinib

[HTML][HTML] Dosing to rash: a phase II trial of the first-line erlotinib for patients with advanced non-small-cell lung cancer an Eastern Cooperative Oncology Group Study  …

JR Brahmer, JW Lee, AM Traynor, MM Hidalgo… - European Journal of …, 2014 - Elsevier
… the current study was that by increasing the dose of erlotinib until … study of erlotinib in the
first-line setting of advanced NSCLC evaluated prospectively if increasing the dose of erlotinib

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… Compared with the efficacy of neoadjuvant PD-1 (CD274 molecule) blockade, the general
pathologic response observed with erlotinib in the current study was unimpressive (MPR, 9.7…

[HTML][HTML] Erlotinib therapy after initial platinum doublet therapy in patients with EGFR wild type non-small cell lung cancer: results of a combined patient-level analysis …

RU Osarogiagbon, F Cappuzzo… - … lung cancer research, 2015 - ncbi.nlm.nih.gov
… The clinical benefit of erlotinib in treating epidermal growth factor receptor (EGFR) wildtype
… of erlotinib in confirmed EGFR wildtype patients in two placebo-controlled phase III trials: the …

[HTML][HTML] … phase II study comparing erlotinib versus erlotinib with alternating chemotherapy in relapsed non-small-cell lung cancer patients: the NVALT-10 study

…, O Dalesio, HJM Groen, EF Smit, NVALT Study Group - Annals of oncology, 2013 - Elsevier
… Although front-line phase III studies testing this concept in advanced NSCLC patients
were negative [3, 4], pharmacodynamic separation of chemotherapy, and EGFR-TKIs were …

Randomized proteomic stratified phase III study of second-line erlotinib (E) versus chemotherapy (CT) in patients with inoperable non-small cell lung cancer (PROSE).

C Lazzari, S Novello, S Barni, M Aieta, F De Marinis… - 2013 - ascopubs.org
LBA8005 Background: Second-line therapy for advanced NSCLC patients (pts) after progression
on platinum-based regimens typically employs CT or E. Improved PFS in E-treated pts …

[HTML][HTML] … beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial

M Schuler, JCH Yang, K Park, JH Kim, J Bennouna… - Annals of …, 2016 - Elsevier
patients were … , this study identified a selected population of patients who achieved a median
of nearly 1 year of clinical benefit following failure of chemotherapy and gefitinib or erlotinib. …

[HTML][HTML] … for the JUNIPER Study: A Randomized Phase III Study of Abemaciclib With Best Supportive Care Versus Erlotinib With Best Supportive Care in Patients With …

JW Goldman, P Shi, M Reck, L Paz-Ares, A Koustenis… - Clinical lung cancer, 2016 - Elsevier
… For patients with KRAS wild type … study design, in which the combination of abemaciclib
with best supportive care (BSC) versus erlotinib with BSC will be evaluated in pretreated patients

[HTML][HTML] SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with hepatocellular carcinoma (HCC)

AX Zhu, O Rosmorduc, J Evans, P Ross, A Santoro… - Annals of …, 2012 - Elsevier
… for participating and enrolling patients in this study M. Leberre: Dr. … Erlotinib is a direct and
reversible EGFR tyrosine kinase inhibitor. Combining sorafenib and erlotinib in HCC patients