Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non–Small-Cell Lung Cancer With EGFR Mutation …

H Tada, T Mitsudomi, T Misumi, K Sugio… - Journal of Clinical …, 2022 - ascopubs.org
phase III study failed to demonstrate the superiority of gefitinib in terms of DFS and OS among
patients with completely resected stage II-III … The EVAN trial is the randomized phase II trial …

Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial

CN Sternberg, ID Davis, J Mardiak… - Journal of clinical …, 2010 - ascopubs.org
… This randomized, double-blind, placebo-controlled phase III study evaluated efficacy and
safety of pazopanib monotherapy in treatment-naive and cytokine-pretreated patients with …

A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer

A Bamias, M Karina, P Papakostas… - Cancer chemotherapy …, 2010 - Springer
The optimal adjuvant treatment for gastric cancer remains controversial. We compared the
efficacy of a docetaxel and platinum adjuvant chemotherapy regimen, in patients with high-…

Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with …

SS Agarwala, J Glaspy, SJ O'Day, M Mitchell… - Journal of clinical …, 2002 - ascopubs.org
… Based on these phase II studies, a phase III, multicenter, randomized trial of patients with …
for any of these approaches has yet to be demonstrated in randomized phase III trials. …

… exploratory analysis of a prospectively randomized phase III study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVAR)

P Wimberger, N Lehmann, R Kimmig, A Burges… - Gynecologic …, 2007 - Elsevier
… documented throughout the multi-center prospective randomized phase III trial (OVAR-3)
of … In this study 798 patients with FIGO IIB–IV were first operated then randomized and …

Randomized phase II designs in cancer clinical trials: current status and future directions

JJ Lee, L Feng - Journal of Clinical Oncology, 2005 - ascopubs.org
… In this review, we evaluate the use of randomized phase II (RPh2) trials in studying multiple
treatment regimens. We are interested in identifying the types of RPh2 designs and how they …

A randomized phase-III study of the efficacy of granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Munster …

K Welte, A Reiter, K Mempel, M Pfetsch, G Schwab… - 1996 - ashpublications.org
… These results are in line with previously published randomized phase-111 studies in
adult patients, which also showed a reduction of infections under r-metHuG-CSF treatment. …

Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2–overexpressing metastatic …

N Robert, B Leyland-Jones, L Asmar, R Belt… - Journal of Clinical …, 2006 - ascopubs.org
Purpose This randomized, multicenter, phase III trial evaluated the efficacy and safety of
trastuzumab and paclitaxel with or without carboplatin as first-line therapy for women with HER-2…

Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trial

AL Cheng, YK Kang, DY Lin, JW Park… - Journal of clinical …, 2013 - ascopubs.org
… the 37.5 mg CDD schedule was selected for further study. In this article, we report findings
from an open-label, phase III study comparing sunitinib versus sorafenib in advanced HCC. …

Single blind randomized phase III trial to investigate the benefit of a focal lesion ablative microboost in prostate cancer (FLAME-trial): study protocol for a randomized …

IM Lips, UA van der Heide, K Haustermans… - Trials, 2011 - Springer
Background The treatment results of external beam radiotherapy for intermediate and high
risk prostate cancer patients are insufficient with five-year biochemical relapse rates of …