… use in imaging, followed by the biological barriers they must bypass to reach the target
cancer cells, including the blood, liver, kidneys, spleen, and particularly the blood-brain barrier. …

… and synthetic PTDs that have evolved in the quest for easier translocation across biological
barriers and the application of these peptide domains to in vivo delivery of imaging agents. …

… biological barriers against nanotherapeutics, synergistic consideration of all these barriers
is … nanocarriers for improving the actual therapeutic effect of nanotherapeutics, in hope that it …

… and therapeutic efficacy are greatly hindered by barriers … cross endothelial cell (EC) barriers
in normal tissues and in solid … cell barrier. Each strategy requires further testing to define its …

… biological barriers and imaging technologies of MNMs. In Section 2, we summarize the
development of MNMs on the crossing of biological barriers … , gastric acid barrier, and vitreous …

… The physics of mass transport within body compartments and across biological barriers …
as imaging contrast enhancers, and can be employed for lesion-selective delivery of therapy. …

… due to the systemic biological barriers, including blood … to systematically overcome all barriers
by the novel design of smart … can address different barriers with intrinsically conflicting and …

… of these barriers for imaging and imaging-guided therapy. … biologic specificity provided by
such molecules is attractive both from an imaging and a therapeutic perspective, the barriers …

… entities with enhanced transport across biological barriers. Thus, POH … of biological barriers
and accordingly shape its multifaceted promise in the drug development for cancer therapy [3…

… for overcoming the numerous biological barriers facing nanomedicines are summarized. …
both physical barriers, such as membrane‐associated efflux pumps, and biological features, …